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ENZYME entry: EC 3.4.21.61

Accepted Name
Kexin.
Alternative Name(s)
Paired-basic endopeptidase.
Prohormone-processing endoprotease.
Proteinase yscF.
Yeast KEX2 protease.
Reaction catalysed
Cleavage of -Lys-Arg-|-Xaa- and -Arg-Arg-|-Xaa- bonds to process yeast alpha-factor pheromone and killer toxin precursors
Comment(s)
  • Calcium activated.
  • Inhibited by p-mercuribenzoate.
  • Belongs to peptidase family S8.
  • Formerly EC 3.4.22.23.
Cross-references
PROSITEPDOC00125
BRENDA3.4.21.61
EC2PDB3.4.21.61
ExplorEnz3.4.21.61
PRIAM enzyme-specific profiles3.4.21.61
KEGG Ligand Database for Enzyme Nomenclature3.4.21.61
IUBMB Enzyme Nomenclature3.4.21.61
IntEnz3.4.21.61
MEDLINEFind literature relating to 3.4.21.61
MetaCyc3.4.21.61
UniProtKB/Swiss-Prot
O13359, KEX2_CANAW;  P13134, KEX2_YEAST;  

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