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ENZYME entry: EC 3.4.21.70

Accepted Name
Pancreatic endopeptidase E.
Alternative Name(s)
Cholesterol-binding proteinase.
Elastase III.
Reaction catalysed
Preferential cleavage: Ala-|-Xaa. Does not hydrolyze elastin
Comment(s)
  • From pancreatic juice.
  • Unlike elastases, has an acidic pI.
  • Binds cholesterol.
  • Belongs to peptidase family S1.
Cross-references
PROSITEPDOC00124
BRENDA3.4.21.70
EC2PDB3.4.21.70
ExplorEnz3.4.21.70
PRIAM enzyme-specific profiles3.4.21.70
KEGG Ligand Database for Enzyme Nomenclature3.4.21.70
IUBMB Enzyme Nomenclature3.4.21.70
IntEnz3.4.21.70
MEDLINEFind literature relating to 3.4.21.70
MetaCyc3.4.21.70
UniProtKB/Swiss-Prot
P09093, CEL3A_HUMAN;  P08861, CEL3B_HUMAN;  O19023, CEL3B_MACMU;  
Q9CQ52, CEL3B_MOUSE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
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