ENZYME entry: EC 3.4.21.72
| Accepted Name |
|---|
| IgA-specific serine endopeptidase.
|
| Alternative Name(s) |
|---|
| IgA protease. |
| Immunoglobulin A1 protease. |
| Reaction catalysed |
|---|
| Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the hinge region. No small molecule substrates are known |
| Comment(s) |
|---|
- Species variants differing slightly in specificity are secreted by
Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus
influenzae.
- Some other bacterial endopeptidases with similar specificity are of
metallotype (see EC 3.4.24.13).
- Belongs to peptidase family S6.
|
| Cross-references |
|---|
| BRENDA | 3.4.21.72 |
| EC2PDB | 3.4.21.72 |
| ExplorEnz | 3.4.21.72 |
| PRIAM enzyme-specific profiles | 3.4.21.72 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.72 |
| IUBMB Enzyme Nomenclature | 3.4.21.72 |
| IntEnz | 3.4.21.72 |
| MEDLINE | Find literature relating to 3.4.21.72 |
| MetaCyc | 3.4.21.72 |
| UniProtKB/Swiss-Prot |
|
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