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ENZYME

ENZYME entry: EC 3.4.21.73

Accepted Name
u-plasminogen activator
Alternative Name(s)
cellular plasminogen activator
urinary plasminogen activator
urokinase
Reaction catalysed
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin
Comment(s)
  • Formed from the inactive precursor by action of plasmin or plasma kallikrein.
  • Differs in structure from EC 3.4.21.68, and does not bind to fibrin.
  • Belongs to peptidase family S1.
  • Formerly EC 3.4.21.31 and EC 3.4.99.26.
Cross-references
BRENDA3.4.21.73
EC2PDB3.4.21.73
ExplorEnz3.4.21.73
PRIAM enzyme-specific profiles3.4.21.73
KEGG Ligand Database for Enzyme Nomenclature3.4.21.73
IUBMB Enzyme Nomenclature3.4.21.73
IntEnz3.4.21.73
MEDLINEFind literature relating to 3.4.21.73
MetaCyc3.4.21.73
Rhea expert-curated reactions3.4.21.73
UniProtKB/Swiss-Prot
Q05589, UROK_BOVINP15120, UROK_CHICKP00749, UROK_HUMAN
P06869, UROK_MOUSEP16227, UROK_PAPCYP04185, UROK_PIG
Q5RF29, UROK_PONABQ8MHY7, UROK_RABITP29598, UROK_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
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