ID 3.4.21.98 DE hepacivirin. AN Cpro-2. AN hepatitis C virus NS3 serine proteinase. CA Hydrolysis of four peptide bonds in the viral precursor polyprotein, CA commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or CA Ala in P1'. CC -!- Encoded by the genome of the viruses of the hepatitis C group, CC and contributes to the maturation of the precursor polyproteins. CC -!- The enzyme is greatly activated by binding of the 54-residue NS4A CC 'cofactor' protein also derived from the viral polyprotein. CC -!- Belongs to peptidase family S29. DR Q69422, POLG_GBVB ; P26664, POLG_HCV1 ; Q5I2N3, POLG_HCV6A ; DR P27958, POLG_HCV77 ; Q68749, POLG_HCVBB ; P26663, POLG_HCVBK ; DR Q9WMX2, POLG_HCVCO ; O39929, POLG_HCVED ; O39927, POLG_HCVEU ; DR O39928, POLG_HCVEV ; Q81754, POLG_HCVH9 ; Q913D4, POLG_HCVIN ; DR Q03463, POLG_HCVJ1 ; O92972, POLG_HCVJ4 ; P26660, POLG_HCVJ6 ; DR P26661, POLG_HCVJ8 ; P26662, POLG_HCVJA ; Q99IB8, POLG_HCVJF ; DR Q68801, POLG_HCVJK ; Q68798, POLG_HCVJL ; Q9DHD6, POLG_HCVJP ; DR Q00269, POLG_HCVJT ; Q81495, POLG_HCVK3 ; Q81258, POLG_HCVNZ ; DR Q913V3, POLG_HCVR6 ; O91936, POLG_HCVSA ; O92529, POLG_HCVT5 ; DR Q81487, POLG_HCVTR ; P29846, POLG_HCVTW ; Q9QAX1, POLG_HCVVA ; DR O92530, POLG_HCVVN ; O92531, POLG_HCVVO ; O92532, POLG_HCVVP ; //