ENZYME entry: EC 3.4.22.1

Accepted Name
Cathepsin B.
Alternative Name(s)
Cathepsin B1.
Reaction catalysed
Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides
Comment(s)
  • An intracellular (lysosomal) enzyme.
  • Belongs to peptidase family C1.
Cross-references
PROSITEPDOC00126
BRENDA3.4.22.1
EC2PDB3.4.22.1
ExplorEnz3.4.22.1
PRIAM enzyme-specific profiles3.4.22.1
KEGG Ligand Database for Enzyme Nomenclature3.4.22.1
IUBMB Enzyme Nomenclature3.4.22.1
IntEnz3.4.22.1
MEDLINEFind literature relating to 3.4.22.1
MetaCyc3.4.22.1
UniProtKB/Swiss-Prot
P07688, CATB_BOVIN;  P43233, CATB_CHICK;  P81494, CATB_COTJA;  
P07858, CATB_HUMAN;  Q4R5M2, CATB_MACFA;  P10605, CATB_MOUSE;  
A1E295, CATB_PIG;  Q5R6D1, CATB_PONAB;  P00787, CATB_RAT;  
P83205, CATB_SHEEP;  Q54QD9, CTSB_DICDI;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-