ID   3.4.22.38
DE   cathepsin K.
AN   cathepsin O.
AN   cathepsin O2.
AN   cathepsin X.
CA   Broad proteolytic activity. With small-molecule substrates and
CA   inhibitors, the major determinant of specificity is P2, which is
CA   preferably Leu, Met > Phe, and not Arg.
CC   -!- Prominently expressed in mammalian osteoclasts, and believed to play
CC       a role in bone resorption.
CC   -!- Belongs to peptidase family C1.
DR   Q5E968, CATK_BOVIN ;  Q3ZKN1, CATK_CANLF ;  Q90686, CATK_CHICK ;
DR   P43235, CATK_HUMAN ;  P61276, CATK_MACFA ;  P61277, CATK_MACMU ;
DR   P55097, CATK_MOUSE ;  Q9GLE3, CATK_PIG   ;  P43236, CATK_RABIT ;
DR   O35186, CATK_RAT   ;
//