ENZYME entry: EC 3.4.22.39

Accepted Name
Adenain.
Reaction catalysed
Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-|-Xaa- and -Yaa-Xaa-Gly-Xaa-|-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid)
Comment(s)
  • A cysteine endopeptidase from adenoviruses.
  • Activity is greatly stimulated by the binding to the enzyme of an 11-residue peptide from the adenovirus capsid protein pre-VI at a site separate from the active site.
  • Belongs to peptidase family C5.
Cross-references
BRENDA3.4.22.39
EC2PDB3.4.22.39
ExplorEnz3.4.22.39
PRIAM enzyme-specific profiles3.4.22.39
KEGG Ligand Database for Enzyme Nomenclature3.4.22.39
IUBMB Enzyme Nomenclature3.4.22.39
IntEnz3.4.22.39
MEDLINEFind literature relating to 3.4.22.39
MetaCyc3.4.22.39
UniProtKB/Swiss-Prot
P03252, ADEN_ADE02;  P10381, ADEN_ADE03;  P07885, ADEN_ADE04;  
P03253, ADEN_ADE05;  Q5TJ03, ADEN_ADE09;  P09569, ADEN_ADE12;  
Q9WF19, ADEN_ADE17;  P11825, ADEN_ADE40;  P11826, ADEN_ADE41;  
Q96629, ADEN_ADEB2;  P19119, ADEN_ADEB3;  O71150, ADEN_ADEB4;  
P19151, ADEN_ADEB7;  O71070, ADEN_ADEBA;  P68984, ADEN_ADECC;  
P68985, ADEN_ADECR;  P87563, ADEN_ADECT;  P68986, ADEN_ADECU;  
O40958, ADEN_ADEE2;  Q9IIH4, ADEN_ADEF1;  P42672, ADEN_ADEG1;  
Q9QM72, ADEN_ADEG8;  P30202, ADEN_ADEM1;  Q83906, ADEN_ADEO7;  
Q84177, ADEN_ADEP3;  Q8JN66, ADEN_ADES1;  

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