ENZYME entry: EC 3.4.22.42

Accepted Name
Cathepsin O.
Reaction catalysed
The recombinant human enzyme hydrolyzes synthetic endopeptidase substrates including Z-Phe-Arg-NHMec and Z-Arg-Arg-NHMec
Comment(s)
  • The recombinant human enzyme is catalytically active at pH 6.0 and is inhibited by compound E-64.
  • Belongs to peptidase family C1.
Cross-references
PROSITEPDOC00126
BRENDA3.4.22.42
EC2PDB3.4.22.42
ExplorEnz3.4.22.42
PRIAM enzyme-specific profiles3.4.22.42
KEGG Ligand Database for Enzyme Nomenclature3.4.22.42
IUBMB Enzyme Nomenclature3.4.22.42
IntEnz3.4.22.42
MEDLINEFind literature relating to 3.4.22.42
MetaCyc3.4.22.42
UniProtKB/Swiss-Prot
P43234, CATO_HUMAN;  Q8BM88, CATO_MOUSE;  

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