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ENZYME

ENZYME entry: EC 3.4.22.52

Accepted Name
calpain-1
Alternative Name(s)
calcium-activated neutral protease I
mu-calpain
Reaction catalysed
Broad endopeptidase specificity
Comment(s)
  • Cytosolic in animal cells.
  • The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC 3.4.22.53.
  • Belongs to peptidase family C2.
  • Formerly EC 3.4.22.17 and EC 3.4.24.5.
Cross-references
BRENDA3.4.22.52
EC2PDB3.4.22.52
ExplorEnz3.4.22.52
PRIAM enzyme-specific profiles3.4.22.52
KEGG Ligand Database for Enzyme Nomenclature3.4.22.52
IUBMB Enzyme Nomenclature3.4.22.52
IntEnz3.4.22.52
MEDLINEFind literature relating to 3.4.22.52
MetaCyc3.4.22.52
Rhea expert-curated reactions3.4.22.52
UniProtKB/Swiss-Prot
Q27970, CAN1_BOVINP07384, CAN1_HUMANQ9GLG2, CAN1_MACFA
O35350, CAN1_MOUSEP35750, CAN1_PIGQ5NVS7, CAN1_PONAB
P06815, CAN1_RABITP97571, CAN1_RATP00789, CANX_CHICK

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.22.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
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