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ENZYME entry: EC 3.4.23.28

Accepted Name
Acrocylindropepsin.
Alternative Name(s)
Acrocylindrium proteinase.
Reaction catalysed
Preference for hydrophobic residue at P1 and P1'. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves 6-Leu-|-Cys(SO(3)H)-7, 21-Glu-|-Arg-22 and 3-Asn-|-Gln-4, although not 4-Gln-|-His-5
Comment(s)
  • From the imperfect fungus Acrocylindrium sp.
  • Has a very low pH optimum on casein of 2.0.
  • Formerly EC 3.4.4.17, EC 3.4.23.6 and EC 3.4.99.1.
Cross-references
BRENDA3.4.23.28
EC2PDB3.4.23.28
ExplorEnz3.4.23.28
PRIAM enzyme-specific profiles3.4.23.28
KEGG Ligand Database for Enzyme Nomenclature3.4.23.28
IUBMB Enzyme Nomenclature3.4.23.28
IntEnz3.4.23.28
MEDLINEFind literature relating to 3.4.23.28
MetaCyc3.4.23.28

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-