ENZYME entry: EC 3.4.23.31
| Accepted Name |
|---|
| Scytalidopepsin A.
|
| Alternative Name(s) |
|---|
| Scytalidium aspartic proteinase A. |
| Reaction catalysed |
|---|
| Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves 7-Cys(SO(3)H)-|-Gly-8 and 17-Leu-|-Val-18 in the B chain of insulin |
| Comment(s) |
|---|
- Isolated from the imperfect fungus Scytalidium lignicolum.
- Not inhibited by pepstatin-Ac, methyl 2-diazoacetamidohexanoate or
1,2-epoxy-3-(p-nitrophenyl)propane.
- A related enzyme from the same organism, proteinase C, is also
insensitive to these inhibitors and has molecular weight 406 kDa.
|
| Cross-references |
|---|
| BRENDA | 3.4.23.31 |
| EC2PDB | 3.4.23.31 |
| ExplorEnz | 3.4.23.31 |
| PRIAM enzyme-specific profiles | 3.4.23.31 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.31 |
| IUBMB Enzyme Nomenclature | 3.4.23.31 |
| IntEnz | 3.4.23.31 |
| MEDLINE | Find literature relating to 3.4.23.31 |
| MetaCyc | 3.4.23.31 |
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UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
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