ENZYME entry: EC 3.4.23.48

Accepted Name
Plasminogen activator Pla.
Alternative Name(s)
Coagulase/fibrinolysin.
Reaction catalysed
Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val-561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins
Comment(s)
  • From the bacterium Yersinia pestis that causes plague.
  • Belongs to peptidase family A26.
Cross-references
BRENDA3.4.23.48
EC2PDB3.4.23.48
ExplorEnz3.4.23.48
PRIAM enzyme-specific profiles3.4.23.48
KEGG Ligand Database for Enzyme Nomenclature3.4.23.48
IUBMB Enzyme Nomenclature3.4.23.48
IntEnz3.4.23.48
MEDLINEFind literature relating to 3.4.23.48
MetaCyc3.4.23.48
UniProtKB/Swiss-Prot
P17811, COLY_YERPE

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