ENZYME entry: EC 3.4.23.5

Accepted Name
Cathepsin D.
Reaction catalysed
Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin
Comment(s)
  • Occurs intracellularly, in lysosomes.
  • Belongs to peptidase family A1.
  • Formerly EC 3.4.4.23.
Cross-references
PROSITEPDOC00128
BRENDA3.4.23.5
EC2PDB3.4.23.5
ExplorEnz3.4.23.5
PRIAM enzyme-specific profiles3.4.23.5
KEGG Ligand Database for Enzyme Nomenclature3.4.23.5
IUBMB Enzyme Nomenclature3.4.23.5
IntEnz3.4.23.5
MEDLINEFind literature relating to 3.4.23.5
MetaCyc3.4.23.5
UniProtKB/Swiss-Prot
P80209, CATD_BOVIN;  Q4LAL9, CATD_CANLF;  Q05744, CATD_CHICK;  
O93428, CATD_CHIHA;  Q9DEX3, CATD_CLUHA;  O76856, CATD_DICDI;  
P07339, CATD_HUMAN;  P18242, CATD_MOUSE;  P00795, CATD_PIG;  
P24268, CATD_RAT;  Q9MZS8, CATD_SHEEP;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.23.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-