ENZYME entry: EC 3.4.23.5
| Accepted Name |
| Cathepsin D.
|
| Reaction catalysed |
| Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin |
| Comment(s) |
- Occurs intracellularly, in lysosomes.
- Belongs to peptidase family A1.
- Formerly EC 3.4.4.23.
|
| Cross-references |
| PROSITE | PDOC00128 |
| BRENDA | 3.4.23.5 |
| EC2PDB | 3.4.23.5 |
| ExplorEnz | 3.4.23.5 |
| PRIAM enzyme-specific profiles | 3.4.23.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.5 |
| IUBMB Enzyme Nomenclature | 3.4.23.5 |
| IntEnz | 3.4.23.5 |
| MEDLINE | Find literature relating to 3.4.23.5 |
| MetaCyc | 3.4.23.5 |
| UniProtKB/Swiss-Prot |
| P80209, CATD_BOVIN; | Q4LAL9, CATD_CANFA; | Q05744, CATD_CHICK; |
| O93428, CATD_CHIHA; | Q9DEX3, CATD_CLUHA; | O76856, CATD_DICDI; |
| P07339, CATD_HUMAN; | P18242, CATD_MOUSE; | P00795, CATD_PIG; |
| P24268, CATD_RAT; | Q9MZS8, CATD_SHEEP; |
|
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