ENZYME entry: EC 3.4.23.50
| Accepted Name |
|---|
| Human endogenous retrovirus K endopeptidase.
|
| Alternative Name(s) |
|---|
| HERV K10 endopeptidase. |
| HERV K10 retropepsin. |
| Human endogenous retrovirus K10 endopeptidase. |
| Human endogenous retrovirus K113 protease. |
| Human retrovirus K10 retropepsin. |
| Reaction catalysed |
|---|
| Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site |
| Comment(s) |
|---|
| Belongs to peptidase family A2.
|
| Cross-references |
|---|
| PROSITE | PDOC00128 |
| BRENDA | 3.4.23.50 |
| EC2PDB | 3.4.23.50 |
| ExplorEnz | 3.4.23.50 |
| PRIAM enzyme-specific profiles | 3.4.23.50 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.23.50 |
| IUBMB Enzyme Nomenclature | 3.4.23.50 |
| IntEnz | 3.4.23.50 |
| MEDLINE | Find literature relating to 3.4.23.50 |
| MetaCyc | 3.4.23.50 |
| UniProtKB/Swiss-Prot |
| P63128, POK4_HUMAN; | P10265, VPK10_HUMAN; | P63129, VPK11_HUMAN; |
| P63131, VPK12_HUMAN; | P63125, VPK17_HUMAN; | P63119, VPK1_HUMAN; |
| Q9Y6I0, VPK2_HUMAN; | P63120, VPK3_HUMAN; | P63127, VPK4_HUMAN; |
| P63121, VPK5_HUMAN; | P63122, VPK6_HUMAN; | P63123, VPK7_HUMAN; |
| P63124, VPK9_HUMAN; |
|
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