ENZYME entry: EC 3.4.23.50

Accepted Name
Human endogenous retrovirus K endopeptidase.
Alternative Name(s)
HERV K10 endopeptidase.
HERV K10 retropepsin.
Human endogenous retrovirus K10 endopeptidase.
Human endogenous retrovirus K113 protease.
Human retrovirus K10 retropepsin.
Reaction catalysed
Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-|-PIVQ- cleavage site
Comment(s)
Belongs to peptidase family A2.
Cross-references
PROSITEPDOC00128
BRENDA3.4.23.50
EC2PDB3.4.23.50
ExplorEnz3.4.23.50
PRIAM enzyme-specific profiles3.4.23.50
KEGG Ligand Database for Enzyme Nomenclature3.4.23.50
IUBMB Enzyme Nomenclature3.4.23.50
IntEnz3.4.23.50
MEDLINEFind literature relating to 3.4.23.50
MetaCyc3.4.23.50
UniProtKB/Swiss-Prot
P63128, POK9_HUMAN;  P63121, VP113_HUMAN;  P63124, VPK04_HUMAN;  
P10265, VPK10_HUMAN;  P63123, VPK18_HUMAN;  P63120, VPK19_HUMAN;  
P63119, VPK21_HUMAN;  P63129, VPK24_HUMAN;  P63125, VPK25_HUMAN;  
Q9Y6I0, VPK6_HUMAN;  P63131, VPK7_HUMAN;  P63122, VPK8_HUMAN;  
P63127, VPK9_HUMAN;  

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