ID   3.4.24.11
DE   Neprilysin.
AN   Endopeptidase-2.
AN   Enkephalinase.
AN   Kidney-brush-border neutral proteinase.
AN   Membrane metalloendopeptidase.
AN   Neutral endopeptidase.
CA   Preferential cleavage of polypeptides between hydrophobic residues,
CA   particularly with Phe or Tyr at P1'.
CF   Zinc.
CC   -!- A membrane-bound glycoprotein widely distributed in animal tissues.
CC   -!- Inhibited by phosphoramidon and thiorphan.
CC   -!- Belongs to peptidase family M13.
PR   PROSITE; PDOC00129;
DR   Q495T6, MMEL1_HUMAN;  Q9JLI3, MMEL1_MOUSE;  P0C1T0, MMEL1_RAT  ;
DR   P08473, NEP_HUMAN  ;  Q61391, NEP_MOUSE  ;  P19621, NEP_PIG    ;
DR   Q5RE69, NEP_PONAB  ;  P08049, NEP_RABIT  ;  P07861, NEP_RAT    ;
//