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ENZYME entry: EC 3.4.24.15

Accepted Name
Thimet oligopeptidase.
Alternative Name(s)
Endo-oligopeptidase A.
Endopeptidase 24.15.
Pz-peptidase.
Soluble metalloendopeptidase.
Reaction catalysed
Preferential cleavage of bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues
Cofactor(s)
Zn(2+).
Comment(s)
  • Thiol compounds activate at low concentrations.
  • Belongs to peptidase family M3.
  • Formerly EC 3.4.22.19 and EC 3.4.99.31.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.15
EC2PDB3.4.24.15
ExplorEnz3.4.24.15
PRIAM enzyme-specific profiles3.4.24.15
KEGG Ligand Database for Enzyme Nomenclature3.4.24.15
IUBMB Enzyme Nomenclature3.4.24.15
IntEnz3.4.24.15
MEDLINEFind literature relating to 3.4.24.15
MetaCyc3.4.24.15
UniProtKB/Swiss-Prot
F4HTQ1, MPRO1_ARATH;  Q1JPJ8, THOP1_BOVIN;  P52888, THOP1_HUMAN;  
Q8C1A5, THOP1_MOUSE;  P47788, THOP1_PIG;  P24155, THOP1_RAT;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.24.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-