ENZYME entry: EC 3.4.24.26
| Accepted Name |
| Pseudolysin.
|
| Alternative Name(s) |
| Pseudomonas aeruginosa neutral metalloproteinase. |
| Pseudomonas elastase. |
| Reaction catalysed |
| Hydrolysis of proteins including elastin, collagen types III and IV, fibronectin and immunoglobulin A, generally with bulky hydrophobic group at P1'. Insulin B chain cleavage pattern identical to that of thermolysin, but specificity differs in other respects |
| Cofactor(s) |
| Calcium; Zinc.
|
| Comment(s) |
- Causes tissue damage.
- Belongs to peptidase family M4.
- Formerly EC 3.4.24.4.
|
| Cross-references |
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.26 |
| EC2PDB | 3.4.24.26 |
| ExplorEnz | 3.4.24.26 |
| PRIAM enzyme-specific profiles | 3.4.24.26 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.26 |
| IUBMB Enzyme Nomenclature | 3.4.24.26 |
| IntEnz | 3.4.24.26 |
| MEDLINE | Find literature relating to 3.4.24.26 |
| MetaCyc | 3.4.24.26 |
| UniProtKB/Swiss-Prot |
|
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