ENZYME entry: EC 3.4.24.29
| Accepted Name |
|---|
| Aureolysin.
|
| Alternative Name(s) |
|---|
| Staphylococcus aureus neutral proteinase. |
| Reaction catalysed |
|---|
| Cleavage of insulin B chain with specificity similar to that of thermolysin, preferring hydrophobic P1' residues. Activates the glutamyl endopeptidase (EC 3.4.21.19) of Staphylococcus aureus |
| Cofactor(s) |
|---|
| Calcium; Zinc.
|
| Comment(s) |
|---|
- Earlier confused with staphylokinase.
- Belongs to peptidase family M4.
- Formerly EC 3.4.24.4 and EC 3.4.99.22.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.29 |
| EC2PDB | 3.4.24.29 |
| ExplorEnz | 3.4.24.29 |
| PRIAM enzyme-specific profiles | 3.4.24.29 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.29 |
| IUBMB Enzyme Nomenclature | 3.4.24.29 |
| IntEnz | 3.4.24.29 |
| MEDLINE | Find literature relating to 3.4.24.29 |
| MetaCyc | 3.4.24.29 |
| UniProtKB/Swiss-Prot |
|
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