ENZYME entry: EC 3.4.24.41
| Accepted Name |
|---|
| Atrolysin B.
|
| Alternative Name(s) |
|---|
| Crotalus atrox metalloendopeptidase b. |
| Hemorrhagic toxin b. |
| Ht-b. |
| Reaction catalysed |
|---|
| Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain; identical to the cleavage of insulin B chain by atrolysin C. Also cleaves Xaa-|-Ser bonds in glucagon |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- From the venom of the western diamondback rattlesnake (Crotalus
atrox).
- Belongs to peptidase family M12B.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.41 |
| EC2PDB | 3.4.24.41 |
| ExplorEnz | 3.4.24.41 |
| PRIAM enzyme-specific profiles | 3.4.24.41 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.41 |
| IUBMB Enzyme Nomenclature | 3.4.24.41 |
| IntEnz | 3.4.24.41 |
| MEDLINE | Find literature relating to 3.4.24.41 |
| MetaCyc | 3.4.24.41 |
| UniProtKB/Swiss-Prot |
|
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