ID   3.4.24.42
DE   atrolysin C.
AN   Crotalus atrox metalloendopeptidase c.
AN   hemorrhagic toxin c.
AN   Ht-c.
CA   Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15,
CA   16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain. With small
CA   molecule substrates prefers hydrophobic residue at P2' and small residue
CA   such as Ala, Gly at P1.
CC   -!- Hemorrhagic endopeptidase from the venom of the western diamondback
CC       rattlesnake (Crotalus atrox).
CC   -!- Exist as two forms, c and d.
CC   -!- Digests type IV collagen.
CC   -!- Phosphoramidon inhibits in the 0.1 mM range.
CC   -!- Hemorrhagic toxin-2 of C.ruber ruber has the same molecular weight
CC       and specificity.
CC   -!- Belongs to peptidase family M12B.
DR   Q90392, VM1AC_CROAT;  P15167, VM1AD_CROAT;
//