ENZYME entry: EC 3.4.24.57

Accepted Name
O-sialoglycoprotein endopeptidase.
Alternative Name(s)
Glycoprotease.
Reaction catalysed
Hydrolysis of O-sialoglycoproteins; cleaves 31-Arg-|-Asp-32 bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated
Comment(s)
  • Inhibited by EDTA (100 mM) and 1,10-phenanthroline.
  • Belongs to peptidase family M22.
Cross-references
PROSITEPDOC00779
BRENDA3.4.24.57
EC2PDB3.4.24.57
ExplorEnz3.4.24.57
PRIAM enzyme-specific profiles3.4.24.57
KEGG Ligand Database for Enzyme Nomenclature3.4.24.57
IUBMB Enzyme Nomenclature3.4.24.57
IntEnz3.4.24.57
MEDLINEFind literature relating to 3.4.24.57
MetaCyc3.4.24.57

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