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ENZYME

ENZYME entry: EC 3.4.24.61

Accepted Name
nardilysin
Alternative Name(s)
N-arginine dibasic convertase
NRD convertase
Reaction catalysed
Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys
Comment(s)
  • Unusually for a metallopeptidase, inhibited by bestatin, amastin and ethylmaleimide.
  • Belongs to peptidase family M16.
Cross-references
BRENDA3.4.24.61
EC2PDB3.4.24.61
ExplorEnz3.4.24.61
PRIAM enzyme-specific profiles3.4.24.61
KEGG Ligand Database for Enzyme Nomenclature3.4.24.61
IUBMB Enzyme Nomenclature3.4.24.61
IntEnz3.4.24.61
MEDLINEFind literature relating to 3.4.24.61
MetaCyc3.4.24.61
Rhea expert-curated reactions3.4.24.61
UniProtKB/Swiss-Prot
F4HNU6, NRDC_ARATHO43847, NRDC_HUMANQ8BHG1, NRDC_MOUSE
Q5R4H6, NRDC_PONABP47245, NRDC_RAT

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