ENZYME entry: EC 3.4.24.61
| Accepted Name |
|---|
| Nardilysin.
|
| Alternative Name(s) |
|---|
| N-arginine dibasic convertase. |
| NRD convertase. |
| Reaction catalysed |
|---|
| Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- Unusually for a metallopeptidase, inhibited by bestatin, amastin and
ethylmaleimide.
- Belongs to peptidase family M16.
|
| Cross-references |
|---|
| PROSITE | PDOC00130 |
| BRENDA | 3.4.24.61 |
| EC2PDB | 3.4.24.61 |
| ExplorEnz | 3.4.24.61 |
| PRIAM enzyme-specific profiles | 3.4.24.61 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.61 |
| IUBMB Enzyme Nomenclature | 3.4.24.61 |
| IntEnz | 3.4.24.61 |
| MEDLINE | Find literature relating to 3.4.24.61 |
| MetaCyc | 3.4.24.61 |
| UniProtKB/Swiss-Prot |
|
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