ENZYME entry: EC 3.4.24.63
| Accepted Name |
|---|
| Meprin B.
|
| Reaction catalysed |
|---|
| Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of 5-His-|-Leu-6, 6-Leu-|-Cys-7, 14-Ala-|-Leu-15 and 19-Cys-|-Gly-20 bonds in insulin B chain |
| Cofactor(s) |
|---|
| Zinc.
|
| Comment(s) |
|---|
- Inhibited by EDTA and 1,10-phenanthroline, but not by phosphoramidon,
captopril or thiorphan.
- Belongs to peptidase family M12A.
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.24.63 |
| EC2PDB | 3.4.24.63 |
| ExplorEnz | 3.4.24.63 |
| PRIAM enzyme-specific profiles | 3.4.24.63 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.63 |
| IUBMB Enzyme Nomenclature | 3.4.24.63 |
| IntEnz | 3.4.24.63 |
| MEDLINE | Find literature relating to 3.4.24.63 |
| MetaCyc | 3.4.24.63 |
| UniProtKB/Swiss-Prot |
|
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