ENZYME entry: EC 3.4.24.64

Accepted Name
Mitochondrial processing peptidase.
Alternative Name(s)
Processing enhancing peptidase.
Reaction catalysed
Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2
Cofactor(s)
Zinc.
Comment(s)
  • Known from the mitochondrial matrix of fungi and mammals.
  • Belongs to peptidase family M16.
  • Formerly EC 3.4.99.41.
Cross-references
PROSITEPDOC00130
BRENDA3.4.24.64
EC2PDB3.4.24.64
ExplorEnz3.4.24.64
PRIAM enzyme-specific profiles3.4.24.64
KEGG Ligand Database for Enzyme Nomenclature3.4.24.64
IUBMB Enzyme Nomenclature3.4.24.64
IntEnz3.4.24.64
MEDLINEFind literature relating to 3.4.24.64
MetaCyc3.4.24.64
UniProtKB/Swiss-Prot
Q9ZU25, MPPA1_ARATH;  O04308, MPPA2_ARATH;  P97997, MPPA_BLAEM;  
Q0P5M8, MPPA_BOVIN;  Q10713, MPPA_HUMAN;  Q9DC61, MPPA_MOUSE;  
P23955, MPPA_NEUCR;  Q5R513, MPPA_PONAB;  P20069, MPPA_RAT;  
O94745, MPPA_SCHPO;  P29677, MPPA_SOLTU;  P11914, MPPA_YEAST;  
Q42290, MPPB_ARATH;  Q00302, MPPB_BLAEM;  Q3SZ71, MPPB_BOVIN;  
Q4W6B5, MPPB_DICDI;  O75439, MPPB_HUMAN;  Q9Y8B5, MPPB_LENED;  
Q9CXT8, MPPB_MOUSE;  P11913, MPPB_NEUCR;  Q5REK3, MPPB_PONAB;  
Q03346, MPPB_RAT;  Q9P7X1, MPPB_SCHPO;  P10507, MPPB_YEAST;  

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