ID 3.4.24.65 DE macrophage elastase. AN matrix metalloproteinase 12. AN metalloelastase. CA Hydrolysis of soluble and insoluble elastin. Specific cleavages are also CA produced at 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in the B chain of CA insulin. CC -!- Belongs to peptidase family M10B. DR P39900, MMP12_HUMAN; P34960, MMP12_MOUSE; P79227, MMP12_RABIT; DR Q63341, MMP12_RAT ; //