ENZYME entry: EC 3.4.24.75

Accepted Name
Lysostaphin.
Alternative Name(s)
Glycyl-glycine endopeptidase.
Reaction catalysed
Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans
Cofactor(s)
Zn(2+).
Comment(s)
  • Lyses cells of Staphylococcus aureus in particular, by its action on the cross-bridge of the cell wall.
  • Belongs to peptidase family M23.
Cross-references
BRENDA3.4.24.75
EC2PDB3.4.24.75
ExplorEnz3.4.24.75
PRIAM enzyme-specific profiles3.4.24.75
KEGG Ligand Database for Enzyme Nomenclature3.4.24.75
IUBMB Enzyme Nomenclature3.4.24.75
IntEnz3.4.24.75
MEDLINEFind literature relating to 3.4.24.75
MetaCyc3.4.24.75
UniProtKB/Swiss-Prot
O05156, ALE1_STACP;  P10547, LSTP_STASI;  P10548, LSTP_STAST;  
O33599, LYTM_STAA8;  Q5HJ99, LYTM_STAAC;  Q99WV0, LYTM_STAAM;  
Q7A7T0, LYTM_STAAN;  Q6GK35, LYTM_STAAR;  Q6GCJ6, LYTM_STAAS;  
Q8NYG1, LYTM_STAAW;  

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