ID   3.4.24.80
DE   membrane-type matrix metalloproteinase-1.
AN   matrix metalloproteinase 14.
CA   Endopeptidase activity. Activates progelatinase A by cleavage of the
CA   propeptide at 37-Asn-|-Leu-38. Other bonds hydrolyzed include
CA   35-Gly-|-Ile-36 in the propeptide of collagenase 3, and 341-Asn-|-Phe-
CA   342, 441-Asp-|-Leu-442 and 354-Gln-|-Thr-355 in the aggrecan
CA   interglobular domain.
CC   -!- Believed to play an important role in the activation of progelatinase
CC       A at cell surfaces.
CC   -!- Belongs to peptidase family M10.
DR   Q9GLE4, MMP14_BOVIN;  P50281, MMP14_HUMAN;  P53690, MMP14_MOUSE;
DR   Q9XT90, MMP14_PIG  ;  Q5RES1, MMP14_PONAB;  Q95220, MMP14_RABIT;
DR   Q10739, MMP14_RAT  ;
//