ID   3.4.24.81
DE   ADAM10 endopeptidase.
AN   Kuzbanian protein.
AN   Myelin-associated disintegrin metalloproteinase.
CA   Endopeptidase of broad specificity.
CF   Zinc.
CC   -!- Partially responsible for the 'alpha-secretase' activity in brain
CC       that degrades the potentially harmful beta-amyloid peptide.
CC   -!- Work with ADAM10-deficient mice supports a role in Notch signaling.
CC   -!- Belongs to peptidase family M12.
PR   PROSITE; PDOC00129;
DR   Q10741, ADA10_BOVIN;  O14672, ADA10_HUMAN;  O35598, ADA10_MOUSE;
DR   O77633, ADA10_PIG  ;  Q10743, ADA10_RAT  ;  Q8JIY1, ADA10_XENLA;
//