ID   3.4.24.83
DE   anthrax lethal factor endopeptidase.
AN   lethal toxin.
CA   Preferred amino acids around the cleavage site can be denoted
CA   BBBBxHx-|-H, in which B denotes Arg or Lys, H denotes a hydrophobic amino
CA   acid, and x is any amino acid. The only known protein substrates are
CA   mitogen-activated protein (MAP) kinase kinases.
CC   -!- From the bacterium Bacilus anthracis that causes anthrax.
CC   -!- One of three proteins that are collectively termed anthrax toxin.
CC   -!- Cleaves several MAP kinase kinases near their N-termini, preventing
CC       them from phosphorylating the downstream mitogen-activated protein
CC       kinases.
CC   -!- Belongs to peptidase family M34.
DR   P15917, LEF_BACAN  ;
//