ENZYME entry: EC 3.4.24.87

Accepted Name
ADAMTS13 endopeptidase.
Alternative Name(s)
ADAMTS VWF cleaving metalloprotease.
ADAMTS13 peptidase.
Upshaw factor.
Von Willebrand factor cleaving protease.
VWF-cleaving protease.
VWF-degrading protease.
Reaction catalysed
The enzyme cleaves the von Willebrand factor at bond Tyr(842)-|-Met(843) within the A2 domain
Comment(s)
Belongs to peptidase family M12.
Cross-references
PROSITEPDOC00129
BRENDA3.4.24.87
EC2PDB3.4.24.87
ExplorEnz3.4.24.87
PRIAM enzyme-specific profiles3.4.24.87
KEGG Ligand Database for Enzyme Nomenclature3.4.24.87
IUBMB Enzyme Nomenclature3.4.24.87
IntEnz3.4.24.87
MEDLINEFind literature relating to 3.4.24.87
MetaCyc3.4.24.87
UniProtKB/Swiss-Prot
Q76LX8, ATS13_HUMAN;  Q769J6, ATS13_MOUSE;  

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