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ENZYME

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ENZYME entry: EC 3.5.1.100

Accepted Name
(R)-amidase
Alternative Name(s)
R-amidase
R-stereospecific amidase
Reaction catalysed
  • (R)-piperazine-2-carboxamide + H2O = (R)-piperazine-2-carboxylate + NH4(+)
  • beta-alaninamide + H2O = beta-alanine + NH4(+)
Comment(s)
  • In addition (R)-piperidine-3-carboxamide is hydrolyzed to (R)- piperidine-3-carboxylic acid and NH3, and (R)-N-tert-butylpiperazine- 2-carboxamide is hydrolyzed to (R)-piperazine-2-carboxylic acid and tert-butylamine with lower activity.
  • The enzyme does not act on the other amide substrates which are hydrolyzed by EC 3.5.1.4 (amidase).
Cross-references
BRENDA3.5.1.100
EC2PDB3.5.1.100
ExplorEnz3.5.1.100
PRIAM enzyme-specific profiles3.5.1.100
KEGG Ligand Database for Enzyme Nomenclature3.5.1.100
IUBMB Enzyme Nomenclature3.5.1.100
IntEnz3.5.1.100
MEDLINEFind literature relating to 3.5.1.100
MetaCyc3.5.1.100
Rhea expert-curated reactions3.5.1.100
UniProtKB/Swiss-Prot
Q75SP7, RSAM_PSESP

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-