Due to maintenance work, this service will not be available from Monday June 27th 5.00 pm until Monday June 27th 9.00 pm CEST.

ENZYME entry: EC 3.5.1.100

Accepted Name
(R)-amidase.
Alternative Name(s)
R-amidase.
R-stereospecific amidase.
Reaction catalysed
  • (R)-piperazine-2-carboxamide + H(2)O <=> (R)-piperazine-2-carboxylate + NH(3)
  • Beta-alaninamide + H(2)O <=> beta-alanine + NH(3)
Comment(s)
  • In addition (R)-piperidine-3-carboxamide is hydrolyzed to (R)- piperidine-3-carboxylic acid and NH(3), and (R)-N-tert- butylpiperazine-2-carboxamide is hydrolyzed to (R)-piperazine-2- carboxylic acid and tert-butylamine with lower activity.
  • The enzyme does not act on the other amide substrates which are hydrolyzed by EC 3.5.1.4 (amidase).
Cross-references
PROSITEPDOC50263
BRENDA3.5.1.100
EC2PDB3.5.1.100
ExplorEnz3.5.1.100
PRIAM enzyme-specific profiles3.5.1.100
KEGG Ligand Database for Enzyme Nomenclature3.5.1.100
IUBMB Enzyme Nomenclature3.5.1.100
IntEnz3.5.1.100
MEDLINEFind literature relating to 3.5.1.100
MetaCyc3.5.1.100
UniProtKB/Swiss-Prot
Q75SP7, RSAM_PSESP

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-