Due to maintenance work, this service will not be available on Monday December 12th between 07.00 am and 9.00 am CEST.

ENZYME entry: EC 3.5.1.104

Accepted Name
Peptidoglycan-N-acetylglucosamine deacetylase.
Alternative Name(s)
N-acetylglucosamine deacetylase.
Peptidoglycan deacetylase.
Peptidoglycan GlcNAc deacetylase.
Peptidoglycan N-acetylglucosamine deacetylase.
Reaction catalysed
Peptidoglycan-N-acetyl-D-glucosamine + H(2)O <=> peptidoglycan-D-glucosamine + acetate
Comment(s)
  • Modification of peptidoglycan by N-deacetylation is an important factor in virulence of Helicobacter pylori, Listeria monocytogenes and Streptococcus suis.
  • The enzyme from Streptococcus pneumoniae is a metalloenzyme using a His-His-Asp zinc-binding triad with a nearby aspartic acid and histidine acting as the catalytic base and acid, respectively.
Cross-references
BRENDA3.5.1.104
EC2PDB3.5.1.104
ExplorEnz3.5.1.104
PRIAM enzyme-specific profiles3.5.1.104
KEGG Ligand Database for Enzyme Nomenclature3.5.1.104
IUBMB Enzyme Nomenclature3.5.1.104
IntEnz3.5.1.104
MEDLINEFind literature relating to 3.5.1.104
MetaCyc3.5.1.104
UniProtKB/Swiss-Prot
D4B5F9, PGDA_ARTBC;  Q8DP63, PGDA_STRR6;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-