ENZYME entry: EC 3.5.1.105

Accepted Name
Chitin disaccharide deacetylase.
Alternative Name(s)
Chitin oligosaccharide amidohydolase.
Chitin oligosaccharide deacetylase.
Chitobiose amidohydolase.
Reaction catalysed
N,N'-diacetylchitobiose + H(2)O <=> N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate
Comment(s)
  • Chitin oligosaccharide deacetylase is a key enzyme in the chitin catabolic cascade of chitinolytic Vibrio strains.
  • Besides being a nutrient, the heterodisaccharide product 4-O- (N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a unique inducer of chitinase production in Vibrio parahemolyticus.
  • In contrast to EC 3.5.1.41 this enzyme is specific for the chitin disaccharide.
  • It also deacetylates the chitin trisaccharide with lower efficiency.
  • No activity with higher polymers of GlcNAc.
Cross-references
BRENDA3.5.1.105
EC2PDB3.5.1.105
ExplorEnz3.5.1.105
PRIAM enzyme-specific profiles3.5.1.105
KEGG Ligand Database for Enzyme Nomenclature3.5.1.105
IUBMB Enzyme Nomenclature3.5.1.105
IntEnz3.5.1.105
MEDLINEFind literature relating to 3.5.1.105
MetaCyc3.5.1.105
UniProtKB/Swiss-Prot
A8AHC4, CHBG_CITK8;  A7ZMK0, CHBG_ECO24;  B7USB4, CHBG_ECO27;  
B7MAU4, CHBG_ECO45;  B7L6K7, CHBG_ECO55;  Q8XE10, CHBG_ECO57;  
B5YQ20, CHBG_ECO5E;  B7NT44, CHBG_ECO7I;  B7MVL2, CHBG_ECO81;  
B7M1E5, CHBG_ECO8A;  C4ZZ89, CHBG_ECOBW;  B1XGJ4, CHBG_ECODH;  
A8A0S5, CHBG_ECOHS;  A1ABR4, CHBG_ECOK1;  Q0TH97, CHBG_ECOL5;  
Q8FH10, CHBG_ECOL6;  B1IPJ7, CHBG_ECOLC;  P37794, CHBG_ECOLI;  
B7N569, CHBG_ECOLU;  B6IBF3, CHBG_ECOSE;  B1LDZ8, CHBG_ECOSM;  
Q1RB62, CHBG_ECOUT;  A4W9L0, CHBG_ENT38;  B7LQ59, CHBG_ESCF3;  
B5XT26, CHBG_KLEP3;  A6T7U7, CHBG_KLEP7;  B4EZQ3, CHBG_PROMH;  
B5F7H6, CHBG_SALA4;  Q57PW7, CHBG_SALCH;  B5FJC2, CHBG_SALDC;  
B5QWH6, CHBG_SALEP;  B5RAY7, CHBG_SALG2;  B4TGF6, CHBG_SALHS;  
B4T4L5, CHBG_SALNS;  Q5PHB3, CHBG_SALPA;  A9N261, CHBG_SALPB;  
C0Q659, CHBG_SALPC;  B5BA58, CHBG_SALPK;  B4TUD7, CHBG_SALSV;  
Q8Z6H0, CHBG_SALTI;  Q8ZPU1, CHBG_SALTY;  Q8L3B9, CHBG_SERMA;  
Q0T4U2, CHBG_SHIF8;  P59746, CHBG_SHIFL;  Q3Z280, CHBG_SHISS;  
A1JKF8, CHBG_YERE8;  A7FFP8, CHBG_YERP3;  Q1C596, CHBG_YERPA;  
B2KA89, CHBG_YERPB;  Q8ZDA6, CHBG_YERPE;  A9R3W4, CHBG_YERPG;  
Q1CKI2, CHBG_YERPN;  A4TL15, CHBG_YERPP;  Q667R4, CHBG_YERPS;  
B1JR86, CHBG_YERPY;  Q6F4N1, DCHI_THEKO;  Q99PX1, DEAA_VIBAL;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
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