ENZYME entry: EC 3.5.1.108

Accepted Name
UDP-3-O-acyl-N-acetylglucosamine deacetylase.
Alternative Name(s)
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase.
UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase.
UDP-3-O-acyl-GlcNAc deacetylase.
Reaction catalysed
UDP-3-O-((3R)-3-hydroxytetradecanoyl)-N-acetyl-alpha-D-glucosamine + H(2)O <=> UDP-3-O-((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + acetate
Cofactor(s)
Zn(2+).
Comment(s)
  • The enzyme catalyzes a committed step in the biosynthesis of lipid A.
  • Formerly EC 3.5.1.n1.
Cross-references
BRENDA3.5.1.108
EC2PDB3.5.1.108
ExplorEnz3.5.1.108
PRIAM enzyme-specific profiles3.5.1.108
KEGG Ligand Database for Enzyme Nomenclature3.5.1.108
IUBMB Enzyme Nomenclature3.5.1.108
IntEnz3.5.1.108
MEDLINEFind literature relating to 3.5.1.108
MetaCyc3.5.1.108
UniProtKB/Swiss-Prot
F4IAT8, LPXC1_ARATH;  P0DKB7, LPXC2_ARATH;  P0DKB8, LPXC3_ARATH;  
P0DKB9, LPXC4_ARATH;  F4IAW1, LPXC5_ARATH;  A1TKD7, LPXC_ACIAC;  
Q6F709, LPXC_ACIAD;  B7GV79, LPXC_ACIB3;  B2I1I9, LPXC_ACIBC;  
B0VNZ3, LPXC_ACIBS;  A3M9X5, LPXC_ACIBT;  B0V9D9, LPXC_ACIBY;  
B9MFQ5, LPXC_ACIET;  B7J3W7, LPXC_ACIF2;  B5ELD7, LPXC_ACIF5;  
A1WBZ9, LPXC_ACISJ;  A3MY96, LPXC_ACTP2;  B3GZL4, LPXC_ACTP7;  
B0BRI3, LPXC_ACTPJ;  A6VQM7, LPXC_ACTSZ;  A0KPW7, LPXC_AERHH;  
A4SI61, LPXC_AERS4;  Q0VRZ6, LPXC_ALCBS;  B6ELH0, LPXC_ALISL;  
Q0A6K9, LPXC_ALKEH;  Q2IPK1, LPXC_ANADE;  A7H914, LPXC_ANADF;  
Q3MH15, LPXC_ANAVT;  O67648, LPXC_AQUAE;  A8EWD3, LPXC_ARCB4;  
Q5P702, LPXC_AROAE;  A1K3V2, LPXC_AZOSB;  C1DQA6, LPXC_AZOVD;  
Q6MKC0, LPXC_BDEBA;  Q7VQI3, LPXC_BLOFL;  Q493P6, LPXC_BLOPB;  
Q2KVH1, LPXC_BORA1;  Q7WFS8, LPXC_BORBR;  Q7W4C0, LPXC_BORPA;  
Q7VUQ9, LPXC_BORPE;  B2S6P7, LPXC_BRUA1;  Q2YLZ2, LPXC_BRUA2;  
Q57C85, LPXC_BRUAB;  A9M683, LPXC_BRUC2;  C0RE63, LPXC_BRUMB;  
Q8YI59, LPXC_BRUME;  A5VRG8, LPXC_BRUO2;  B0CHL2, LPXC_BRUSI;  
Q8FZP9, LPXC_BRUSU;  B1YST1, LPXC_BURA4;  Q1BZF6, LPXC_BURCA;  
B1JV85, LPXC_BURCC;  A0K493, LPXC_BURCH;  B4E5Y5, LPXC_BURCJ;  
Q0BIJ4, LPXC_BURCM;  Q39JW3, LPXC_BURL3;  A9AI89, LPXC_BURM1;  
A3MR71, LPXC_BURM7;  A2S5T7, LPXC_BURM9;  Q62GT5, LPXC_BURMA;  
A1V0R0, LPXC_BURMS;  A3NZK8, LPXC_BURP0;  Q3JNE6, LPXC_BURP1;  
A3NDV6, LPXC_BURP6;  Q63QK4, LPXC_BURPS;  Q2SZH6, LPXC_BURTA;  
A4JBA1, LPXC_BURVG;  A7ZC65, LPXC_CAMC1;  A7GZZ5, LPXC_CAMC5;  
A0RQZ8, LPXC_CAMFF;  A7I3V4, LPXC_CAMHC;  A8FJT7, LPXC_CAMJ8;  
A7H1L1, LPXC_CAMJD;  Q9PIZ5, LPXC_CAMJE;  A1VXL5, LPXC_CAMJJ;  
Q5HX34, LPXC_CAMJR;  B9KEU6, LPXC_CAMLR;  B3PCL2, LPXC_CELJU;  
Q5L725, LPXC_CHLAB;  Q824Q4, LPXC_CHLCV;  Q252U8, LPXC_CHLFF;  
Q9PJK9, LPXC_CHLMU;  Q9Z7Q2, LPXC_CHLPN;  B0B8A7, LPXC_CHLT2;  
Q3KLG4, LPXC_CHLTA;  B0B9Y6, LPXC_CHLTB;  O84538, LPXC_CHLTR;  
Q1QVH3, LPXC_CHRSD;  Q7NQ05, LPXC_CHRVO;  A8ALK0, LPXC_CITK8;  
Q47VR7, LPXC_COLP3;  B6J5J6, LPXC_COXB1;  B6J2P6, LPXC_COXB2;  
A9KEQ6, LPXC_COXBN;  A9NA51, LPXC_COXBR;  Q83F11, LPXC_COXBU;  
A7MQ65, LPXC_CROS8;  Q1LIN3, LPXC_CUPMC;  Q0K6N1, LPXC_CUPNH;  
Q46X01, LPXC_CUPNJ;  B3R6V2, LPXC_CUPTR;  Q9TLX3, LPXC_CYACA;  
B7KKQ2, LPXC_CYAP7;  Q47AB0, LPXC_DECAR;  A9BUL2, LPXC_DELAS;  
Q30X16, LPXC_DESAG;  Q727D8, LPXC_DESVH;  A7ZHI7, LPXC_ECO24;  
B7UIE6, LPXC_ECO27;  B7MAL9, LPXC_ECO45;  B7LFW6, LPXC_ECO55;  
P0A727, LPXC_ECO57;  B5YZD2, LPXC_ECO5E;  B7NHK2, LPXC_ECO7I;  
B7MNV5, LPXC_ECO81;  B7M139, LPXC_ECO8A;  C4ZRJ1, LPXC_ECOBW;  
B1XC73, LPXC_ECODH;  A7ZW48, LPXC_ECOHS;  A1A7E1, LPXC_ECOK1;  
Q0TLP3, LPXC_ECOL5;  P0A726, LPXC_ECOL6;  B1IR82, LPXC_ECOLC;  
P0A725, LPXC_ECOLI;  B7N7W9, LPXC_ECOLU;  B6HZ74, LPXC_ECOSE;  
B1LG33, LPXC_ECOSM;  Q1RG99, LPXC_ECOUT;  C5B9G2, LPXC_EDWI9;  
A4W6J9, LPXC_ENT38;  B2VD67, LPXC_ERWT9;  B7LWG2, LPXC_ESCF3;  
Q14JP5, LPXC_FRAT1;  A7NET5, LPXC_FRATF;  Q2A186, LPXC_FRATH;  
Q0BK05, LPXC_FRATO;  Q5NI92, LPXC_FRATT;  A4J049, LPXC_FRATW;  
B5EFL8, LPXC_GEOBB;  C6E4T9, LPXC_GEOSM;  A5GA17, LPXC_GEOUR;  
Q7VMY6, LPXC_HAEDU;  Q4QLF2, LPXC_HAEI8;  A5UCW3, LPXC_HAEIE;  
A5UIR8, LPXC_HAEIG;  P45070, LPXC_HAEIN;  B8F3C2, LPXC_HAEPS;  
Q0I1C7, LPXC_HAES1;  Q2S9Z8, LPXC_HAHCH;  A1WYT6, LPXC_HALHL;  
C4K730, LPXC_HAMD5;  Q7VHF2, LPXC_HELHP;  Q1CUB0, LPXC_HELPH;  
Q9ZM50, LPXC_HELPJ;  O25692, LPXC_HELPY;  B0US73, LPXC_HISS2;  
Q5R0M7, LPXC_IDILO;  B5Y1U1, LPXC_KLEP3;  A6T4N9, LPXC_KLEP7;  
C1D5L0, LPXC_LARHH;  Q1MQP6, LPXC_LAWIP;  Q5X1T2, LPXC_LEGPA;  
A5IAW8, LPXC_LEGPC;  Q5ZSB1, LPXC_LEGPH;  Q5WTJ3, LPXC_LEGPL;  
B0S9V0, LPXC_LEPBA;  Q04T70, LPXC_LEPBJ;  Q051J2, LPXC_LEPBL;  
B0SS82, LPXC_LEPBP;  Q72RV5, LPXC_LEPIC;  Q8F3U4, LPXC_LEPIN;  
Q2W0G6, LPXC_MAGSA;  Q65RZ4, LPXC_MANSM;  A1U3F2, LPXC_MARHV;  
A6VYJ2, LPXC_MARMS;  Q604W4, LPXC_METCA;  Q1GZ08, LPXC_METFK;  
Q1D2K0, LPXC_MYXXD;  B9L6E8, LPXC_NAUPA;  Q5F569, LPXC_NEIG1;  
A9LZR8, LPXC_NEIM0;  Q9JWS2, LPXC_NEIMA;  Q9K1Q3, LPXC_NEIMB;  
A1KR52, LPXC_NEIMF;  Q3J796, LPXC_NITOC;  A6Q223, LPXC_NITSB;  
B2IWK6, LPXC_NOSP7;  Q8YUR5, LPXC_NOSS1;  B2JHF3, LPXC_PARP8;  
B2SYW8, LPXC_PARPJ;  Q13TZ9, LPXC_PARXL;  Q9CPA5, LPXC_PASMU;  
Q6D0I9, LPXC_PECAS;  Q3A225, LPXC_PELCD;  B4RFF2, LPXC_PHEZH;  
Q7N153, LPXC_PHOLL;  Q6LMG1, LPXC_PHOPR;  A4SV81, LPXC_POLAQ;  
A1VST0, LPXC_POLNA;  B1XT16, LPXC_POLNS;  Q12EK9, LPXC_POLSJ;  
B4F105, LPXC_PROMH;  Q48EG4, LPXC_PSE14;  Q15Q23, LPXC_PSEA6;  
A6VB79, LPXC_PSEA7;  B7UZI4, LPXC_PSEA8;  Q02H34, LPXC_PSEAB;  
P47205, LPXC_PSEAE;  Q1I5C4, LPXC_PSEE4;  Q4K6J9, LPXC_PSEF5;  
C3KDE0, LPXC_PSEFS;  Q3IFY6, LPXC_PSEHT;  A4XQT0, LPXC_PSEMY;  
A5W8P4, LPXC_PSEP1;  Q3K750, LPXC_PSEPF;  B0KFS0, LPXC_PSEPG;  
Q88N71, LPXC_PSEPK;  B1J3I7, LPXC_PSEPW;  Q87WZ1, LPXC_PSESM;  
Q4ZNZ6, LPXC_PSEU2;  Q4FQW6, LPXC_PSYA2;  Q1Q950, LPXC_PSYCK;  
A5WCU4, LPXC_PSYWF;  B2UCX0, LPXC_RALPJ;  Q9KHL6, LPXC_RALSO;  
Q21SY0, LPXC_RHOFT;  C3PMV2, LPXC_RICAE;  A8GWA4, LPXC_RICB8;  
Q1RHX9, LPXC_RICBR;  A8EY05, LPXC_RICCK;  Q92IT1, LPXC_RICCN;  
Q4UKP8, LPXC_RICFE;  Q9ZDS1, LPXC_RICPR;  Q68XB5, LPXC_RICTY;  
A1AW96, LPXC_RUTMC;  Q21MG3, LPXC_SACD2;  B5F7X0, LPXC_SALA4;  
A9MQB6, LPXC_SALAR;  Q57TC4, LPXC_SALCH;  B5FI78, LPXC_SALDC;  
B5R2N0, LPXC_SALEP;  B5RH70, LPXC_SALG2;  B4TJ93, LPXC_SALHS;  
B4SU56, LPXC_SALNS;  Q5PDD1, LPXC_SALPA;  A9MZM5, LPXC_SALPB;  
C0Q5J2, LPXC_SALPC;  B5BLC8, LPXC_SALPK;  B4TXI4, LPXC_SALSV;  
Q8Z9G5, LPXC_SALTI;  Q8ZRT9, LPXC_SALTY;  A1S2G4, LPXC_SHEAM;  
B8E6A3, LPXC_SHEB2;  A3CZM6, LPXC_SHEB5;  A6WID6, LPXC_SHEB8;  
A9KY34, LPXC_SHEB9;  Q12SC1, LPXC_SHEDO;  Q07WJ0, LPXC_SHEFN;  
B0TQP2, LPXC_SHEHH;  A3QIL6, LPXC_SHELP;  Q8E9Q2, LPXC_SHEON;  
A8H979, LPXC_SHEPA;  A4Y2P1, LPXC_SHEPC;  B8CNL6, LPXC_SHEPW;  
A0L1N7, LPXC_SHESA;  A8FQA5, LPXC_SHESH;  Q0HE88, LPXC_SHESM;  
Q0HZR1, LPXC_SHESR;  A1RF01, LPXC_SHESW;  Q9EV47, LPXC_SHEVD;  
B1KKX2, LPXC_SHEWM;  B2U2A1, LPXC_SHIB3;  Q326D9, LPXC_SHIBS;  
Q32JZ6, LPXC_SHIDS;  Q0T8A1, LPXC_SHIF8;  P0A728, LPXC_SHIFL;  
Q3Z5R3, LPXC_SHISS;  Q2NVU6, LPXC_SODGM;  Q029X9, LPXC_SOLUE;  
B4SJY1, LPXC_STRM5;  B2FPA9, LPXC_STRMK;  Q30ST0, LPXC_SULDN;  
A6QBQ9, LPXC_SULNB;  Q2LVE4, LPXC_SYNAS;  P72988, LPXC_SYNY3;  
C5BP28, LPXC_TERTT;  Q8DI02, LPXC_THEEB;  B5YKK1, LPXC_THEYD;  
Q31I39, LPXC_THICR;  Q3SMG6, LPXC_THIDA;  B8GMN6, LPXC_THISH;  
C4LA30, LPXC_TOLAT;  C5CNG0, LPXC_VARPS;  A1WI31, LPXC_VEREI;  
A5CWY8, LPXC_VESOH;  A5F5P3, LPXC_VIBC3;  A7MXQ6, LPXC_VIBCB;  
Q9KPH2, LPXC_VIBCH;  C3LQU1, LPXC_VIBCM;  Q5E2Q6, LPXC_VIBF1;  
Q87SF9, LPXC_VIBPA;  B7VJ08, LPXC_VIBTL;  Q8DEL6, LPXC_VIBVU;  
Q7MNU6, LPXC_VIBVY;  Q8D300, LPXC_WIGBR;  Q7M7X7, LPXC_WOLSU;  
Q8PPA3, LPXC_XANAC;  Q3BXE6, LPXC_XANC5;  Q4UQX6, LPXC_XANC8;  
B0RV99, LPXC_XANCB;  Q8PCJ5, LPXC_XANCP;  Q2NZC4, LPXC_XANOM;  
B2SNZ9, LPXC_XANOP;  Q5GW46, LPXC_XANOR;  Q9PF75, LPXC_XYLFA;  
Q87AG5, LPXC_XYLFT;  A7FM60, LPXC_YERP3;  Q8ZIE3, LPXC_YERPE;  
Q66EJ9, LPXC_YERPS;  Q8A015, LPXZ_BACTN;  Q8KBX0, LPXZ_CHLTE;  
Q7MXT8, LPXZ_PORGI;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-