ENZYME entry: EC 3.5.1.117

Accepted Name
6-aminohexanoate-oligomer endohydrolase.
Alternative Name(s)
6-aminohexanoate oligomer hydrolase.
Endo-type 6-aminohexanoate oligomer hydrolase.
Nylon hydrolase.
Nylon-6 hydrolase.
Nylon-oligomer hydrolase.
Reaction catalysed
(N-(6-aminohexanoyl))(n) + H(2)O <=> (N-(6-aminohexanoyl))(n-x) + (N-(6-aminohexanoyl))(x)
Comment(s)
  • The enzyme is involved in degradation of nylon-6 oligomers.
  • It degrades linear or cyclic oligomers of poly(6-aminohexanoate) with a degree of polymerization greater than three (n > 3) by endo-type cleavage, to oligomers of a length of two or more (2 <= x < n).
  • It shows negligible activity with N-(6-aminohexanoyl)-6- aminohexanoate (cf. EC 3.5.1.46) or with 1,8-diazacyclotetradecane- 2,9-dione (cf. EC 3.5.2.12).
Cross-references
BRENDA3.5.1.117
EC2PDB3.5.1.117
ExplorEnz3.5.1.117
PRIAM enzyme-specific profiles3.5.1.117
KEGG Ligand Database for Enzyme Nomenclature3.5.1.117
IUBMB Enzyme Nomenclature3.5.1.117
IntEnz3.5.1.117
MEDLINEFind literature relating to 3.5.1.117
MetaCyc3.5.1.117

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