ENZYME entry: EC 3.5.1.79
| Accepted Name |
|---|
| Phthalyl amidase.
|
| Alternative Name(s) |
|---|
| o-phthalyl amidase. |
| Reaction catalysed |
|---|
| A phthalylamide + H(2)O <=> phthalic acid + a substituted amine |
| Comment(s) |
|---|
- Phthalyl is used to mean 2-carboxybenzoyl.
- The enzyme from Xanthobacter agilis hydrolyzes phthalylated amino
acids, peptides, beta-lactams, aromatic and aliphatic amines.
- The substituent on nitrogen may be an alkyl group, but may also be
complex, giving an amino acid or peptide derivative.
- Substitutions on the phthalyl ring include 6-F, 6-NH(2), 3-OH, and a
nitrogen in the aromatic ring ortho to the carboxy group attached to
the amine.
|
| Cross-references |
|---|
| BRENDA | 3.5.1.79 |
| EC2PDB | 3.5.1.79 |
| ExplorEnz | 3.5.1.79 |
| PRIAM enzyme-specific profiles | 3.5.1.79 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.1.79 |
| IUBMB Enzyme Nomenclature | 3.5.1.79 |
| IntEnz | 3.5.1.79 |
| MEDLINE | Find literature relating to 3.5.1.79 |
| MetaCyc | 3.5.1.79 |
| UniProtKB/Swiss-Prot |
|
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