ENZYME entry: EC 3.5.1.84
| Accepted Name |
|---|
| Biuret amidohydrolase.
|
| Reaction catalysed |
|---|
| Biuret + H(2)O <=> urea-1-carboxylate + NH(3) |
| Comment(s) |
|---|
- Along with EC 3.5.2.15 and EC 3.5.1.54, this enzyme forms part of the
cyanuric-acid metabolism pathway, which degrades s-triazide
herbicides, such as atrazine (2-chloro-4-(ethylamino)-6-
(isopropylamino)-1,3,5-triazine), in bacteria.
- Urea-1-carboxylate rather than urea (as was thought previously) is
the 2-nitrogen intermediate in cyanuric-acid metabolism in bacteria.
- The product, urea-1-carboxylate, can spontaneously decarboxylate
under acidic conditions to form urea but, under physiological
conditions, it can be converted into CO(2) and ammonia by the action
of EC 3.5.1.54.
|
| Cross-references |
|---|
| BRENDA | 3.5.1.84 |
| EC2PDB | 3.5.1.84 |
| ExplorEnz | 3.5.1.84 |
| PRIAM enzyme-specific profiles | 3.5.1.84 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.1.84 |
| IUBMB Enzyme Nomenclature | 3.5.1.84 |
| IntEnz | 3.5.1.84 |
| MEDLINE | Find literature relating to 3.5.1.84 |
| MetaCyc | 3.5.1.84 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-