ENZYME entry: EC 3.5.1.92

Accepted Name
Pantetheine hydrolase.
Alternative Name(s)
Pantetheinase.
Vanin-1.
Reaction catalysed
(R)-pantetheine + H(2)O <=> (R)-pantothenate + 2-aminoethanethiol
Comment(s)
  • Hydrolyzes only one of the amide bonds of pantetheine.
  • The substrate analogs phosphopantetheine and CoA are not substrates.
  • Recycles pantothenate (vitamin B(5)) and produces cysteamine, a potent anti-oxidant.
Cross-references
PROSITEPDOC50263
BRENDA3.5.1.92
EC2PDB3.5.1.92
ExplorEnz3.5.1.92
PRIAM enzyme-specific profiles3.5.1.92
KEGG Ligand Database for Enzyme Nomenclature3.5.1.92
IUBMB Enzyme Nomenclature3.5.1.92
IntEnz3.5.1.92
MEDLINEFind literature relating to 3.5.1.92
MetaCyc3.5.1.92
UniProtKB/Swiss-Prot
Q58CQ9, VNN1_BOVIN;  Q9TSX8, VNN1_CANFA;  O95497, VNN1_HUMAN;  
Q9Z0K8, VNN1_MOUSE;  Q9BDJ5, VNN1_PIG;  O95498, VNN2_HUMAN;  
Q9NY84, VNN3_HUMAN;  Q9QZ25, VNN3_MOUSE;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-