ENZYME entry: EC 3.5.1.93

Accepted Name
Glutaryl-7-aminocephalosporanic-acid acylase.
Alternative Name(s)
7-beta-(4-carboxybutanamido)cephalosporanic acid acylase.
CA.
Cephalosporin acylase.
Cephalosporin C acylase.
GA.
GCA.
GL-7-ACA acylase.
Glutaryl-7-ACA acylase.
Glutaryl-7-aminocephalosporanic acid acylase.
Reaction catalysed
(7R)-7-(4-carboxybutanamido)cephalosporanate + H(2)O <=> (7R)-7-aminocephalosporanate + glutarate
Comment(s)
  • Forms 7-aminocephalosporanic acid, a key intermediate in the synthesis of cephem antibiotics.
  • It reacts only weakly with cephalosporin C.
Cross-references
BRENDA3.5.1.93
EC2PDB3.5.1.93
ExplorEnz3.5.1.93
PRIAM enzyme-specific profiles3.5.1.93
KEGG Ligand Database for Enzyme Nomenclature3.5.1.93
IUBMB Enzyme Nomenclature3.5.1.93
IntEnz3.5.1.93
MEDLINEFind literature relating to 3.5.1.93
MetaCyc3.5.1.93
UniProtKB/Swiss-Prot
Q9L5D6, G7AC_BREDI;  P07662, G7AC_PSEU7;  P15557, PAC1_PSES3;  
Q05053, PAC1_PSESV;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-