ENZYME entry: EC 3.5.1.93
| Accepted Name |
|---|
| Glutaryl-7-aminocephalosporanic-acid acylase.
|
| Alternative Name(s) |
|---|
| 7-beta-(4-carboxybutanamido)cephalosporanic acid acylase. |
| CA. |
| Cephalosporin acylase. |
| Cephalosporin C acylase. |
| GA. |
| GCA. |
| GL-7-ACA acylase. |
| Glutaryl-7-ACA acylase. |
| Glutaryl-7-aminocephalosporanic acid acylase. |
| Reaction catalysed |
|---|
| (7R)-7-(4-carboxybutanamido)cephalosporanate + H(2)O <=> (7R)-7-aminocephalosporanate + glutarate |
| Comment(s) |
|---|
- Forms 7-aminocephalosporanic acid, a key intermediate in the
synthesis of cephem antibiotics.
- It reacts only weakly with cephalosporin C.
|
| Cross-references |
|---|
| BRENDA | 3.5.1.93 |
| EC2PDB | 3.5.1.93 |
| ExplorEnz | 3.5.1.93 |
| PRIAM enzyme-specific profiles | 3.5.1.93 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.1.93 |
| IUBMB Enzyme Nomenclature | 3.5.1.93 |
| IntEnz | 3.5.1.93 |
| MEDLINE | Find literature relating to 3.5.1.93 |
| MetaCyc | 3.5.1.93 |
| UniProtKB/Swiss-Prot |
|
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