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ENZYME

ENZYME entry: EC 3.5.1.93

Accepted Name
glutaryl-7-aminocephalosporanic-acid acylase
Alternative Name(s)
7beta-(4-carboxybutanamido)cephalosporanic acid acylase
CA
cephalosporin acylase
cephalosporin C acylase
GA
GCA
GL-7-ACA acylase
glutaryl-7-ACA acylase
glutaryl-7-aminocephalosporanic acid acylase
Reaction catalysed
(7R)-7-(4-carboxybutanamido)cephalosporanate + H2O <=> (7R)-7-aminocephalosporanate + glutarate
Comment(s)
  • Forms 7-aminocephalosporanic acid, a key intermediate in the synthesis of cephem antibiotics.
  • It reacts only weakly with cephalosporin C.
Cross-references
BRENDA3.5.1.93
EC2PDB3.5.1.93
ExplorEnz3.5.1.93
PRIAM enzyme-specific profiles3.5.1.93
KEGG Ligand Database for Enzyme Nomenclature3.5.1.93
IUBMB Enzyme Nomenclature3.5.1.93
IntEnz3.5.1.93
MEDLINEFind literature relating to 3.5.1.93
MetaCyc3.5.1.93
Rhea expert-curated reactions3.5.1.93
UniProtKB/Swiss-Prot
Q9L5D6, G7AC_BREDIP07662, G7AC_PSEU7P15557, PAC1_PSES3
Q05053, PAC1_PSESV

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-