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ENZYME entry: EC

Accepted Name
Gamma-glutamyl-gamma-aminobutyrate hydrolase.
Alternative Name(s)
Gamma-glutamyl-GABA hydrolase.
Reaction catalysed
4-(gamma-L-glutamylamino)butanoate + H(2)O <=> 4-aminobutanoate + L-glutamate
  • Forms part of a novel putrescine-utilizing pathway in Escherichia coli, in which it has been hypothesized that putrescine is first glutamylated to form gamma-glutamylputrescine, which is oxidized to 4-(gamma-glutamylamino)butanal and then to 4-(gamma- glutamylamino)butanoate.
  • Also can catalyze the reactions of EC and EC
PRIAM enzyme-specific profiles3.5.1.94
KEGG Ligand Database for Enzyme Nomenclature3.5.1.94
IUBMB Enzyme Nomenclature3.5.1.94
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