ENZYME entry: EC 3.5.2.15
| Accepted Name |
|---|
| Cyanuric acid amidohydrolase.
|
| Reaction catalysed |
|---|
| Cyanuric acid + H(2)O <=> biuret + CO(2) |
| Comment(s) |
|---|
- Along with EC 3.5.1.54 and EC 3.5.1.84, forms part of the cyanuric-
acid metabolism pathway, which degrades s-triazide herbicides, such
as atrazine (2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-
triazine), in bacteria.
- A key enzyme in the pathway, catalyzing the ring cleavage of cyanuric
acid.
- Specific for cyanuric acid as substrate as neither the structurally
related compounds ammeline (2,4-diamino-6-hydroxy-s-triazine) and
ammelide (2-amino-4,6-dihydroxy-s-triazine) nor a number of
pyrimidine compounds, such as uracil and cytosine, can act as
substrates.
|
| Cross-references |
|---|
| BRENDA | 3.5.2.15 |
| EC2PDB | 3.5.2.15 |
| ExplorEnz | 3.5.2.15 |
| PRIAM enzyme-specific profiles | 3.5.2.15 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.2.15 |
| IUBMB Enzyme Nomenclature | 3.5.2.15 |
| IntEnz | 3.5.2.15 |
| MEDLINE | Find literature relating to 3.5.2.15 |
| MetaCyc | 3.5.2.15 |
| UniProtKB/Swiss-Prot |
|
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