ENZYME entry: EC 3.5.2.3

Accepted Name
Dihydroorotase.
Alternative Name(s)
Carbamoylaspartic dehydrase.
DHOase.
Reaction catalysed
(S)-dihydroorotate + H(2)O <=> N-carbamoyl-L-aspartate
Cross-references
PROSITEPDOC00401
BRENDA3.5.2.3
EC2PDB3.5.2.3
ExplorEnz3.5.2.3
PRIAM enzyme-specific profiles3.5.2.3
KEGG Ligand Database for Enzyme Nomenclature3.5.2.3
IUBMB Enzyme Nomenclature3.5.2.3
IntEnz3.5.2.3
MEDLINEFind literature relating to 3.5.2.3
MetaCyc3.5.2.3
UniProtKB/Swiss-Prot
P20054, PYR1_DICDI;  P05990, PYR1_DROME;  P27708, PYR1_HUMAN;  
P08955, PYR1_MESAU;  B2RQC6, PYR1_MOUSE;  Q91437, PYR1_SQUAC;  
B0CF78, PYRC_ACAM1;  Q6FD29, PYRC_ACIAD;  B7GX48, PYRC_ACIB3;  
B7I9G6, PYRC_ACIB5;  B2HWF6, PYRC_ACIBC;  B0VKW9, PYRC_ACIBS;  
A3M3K3, PYRC_ACIBT;  B0VAC1, PYRC_ACIBY;  A1WC79, PYRC_ACISJ;  
Q9YFI5, PYRC_AERPE;  B9J8H5, PYRC_AGRRK;  Q8UI99, PYRC_AGRT5;  
B9JQV9, PYRC_AGRVS;  Q0VNK6, PYRC_ALCBS;  B6ER91, PYRC_ALISL;  
Q0AB36, PYRC_ALKEH;  B8JAE8, PYRC_ANAD2;  Q2IIB0, PYRC_ANADE;  
Q2GL89, PYRC_ANAPZ;  B4UDQ2, PYRC_ANASK;  B7GFA5, PYRC_ANOFW;  
O66990, PYRC_AQUAE;  O04904, PYRC_ARATH;  O28034, PYRC_ARCFU;  
Q5P6Y5, PYRC_AROAE;  A1K3T5, PYRC_AZOSB;  C1DQV1, PYRC_AZOVD;  
C3P658, PYRC_BACAA;  C3L738, PYRC_BACAC;  A0RHR0, PYRC_BACAH;  
Q81WF0, PYRC_BACAN;  B7JJX5, PYRC_BACC0;  Q732I1, PYRC_BACC1;  
B7IUP8, PYRC_BACC2;  C1EPQ2, PYRC_BACC3;  B7H6M4, PYRC_BACC4;  
B7HLM2, PYRC_BACC7;  P46538, PYRC_BACCL;  A7GRL3, PYRC_BACCN;  
B9IVW5, PYRC_BACCQ;  Q819S1, PYRC_BACCR;  Q636D8, PYRC_BACCZ;  
Q9K9V7, PYRC_BACHD;  Q6HES6, PYRC_BACHK;  Q65JU9, PYRC_BACLD;  
A8FD15, PYRC_BACP2;  Q5WFJ0, PYRC_BACSK;  P25995, PYRC_BACSU;  
A9VTC8, PYRC_BACWK;  C0ZG41, PYRC_BREBN;  B8D9C1, PYRC_BUCA5;  
P57416, PYRC_BUCAI;  Q8K9L2, PYRC_BUCAP;  B8D7M3, PYRC_BUCAT;  
B9MS22, PYRC_CALBD;  A4XKT2, PYRC_CALS8;  Q3AC01, PYRC_CARHZ;  
Q11IA4, PYRC_CHESB;  Q8KDK5, PYRC_CHLTE;  A8AI14, PYRC_CITK8;  
Q97LN7, PYRC_CLOAB;  B2UW91, PYRC_CLOBA;  B2TNG1, PYRC_CLOBB;  
B8I770, PYRC_CLOCE;  A3DE07, PYRC_CLOTH;  Q8NQ39, PYRC_CORGL;  
A9NA67, PYRC_COXBR;  A7MG30, PYRC_CROS8;  Q0KEE2, PYRC_CUPNH;  
Q475T7, PYRC_CUPPJ;  B2AH54, PYRC_CUPTR;  Q9RVC3, PYRC_DEIRA;  
A9BSM4, PYRC_DELAS;  C0QJ54, PYRC_DESAH;  Q6AS41, PYRC_DESPS;  
A4J556, PYRC_DESRM;  A7ZKG7, PYRC_ECO24;  B7UP76, PYRC_ECO27;  
B7MIK3, PYRC_ECO45;  B7LFZ6, PYRC_ECO55;  Q8X8N8, PYRC_ECO57;  
B5YVT2, PYRC_ECO5E;  B7NL72, PYRC_ECO7I;  B7MTJ3, PYRC_ECO81;  
B7M937, PYRC_ECO8A;  C4ZS02, PYRC_ECOBW;  B1X9H5, PYRC_ECODH;  
A7ZZ20, PYRC_ECOHS;  A1A9V7, PYRC_ECOK1;  Q0TJ12, PYRC_ECOL5;  
Q8FIR2, PYRC_ECOL6;  B1IV40, PYRC_ECOLC;  P05020, PYRC_ECOLI;  
B7NAT7, PYRC_ECOLU;  B6I9D9, PYRC_ECOSE;  B1LIU8, PYRC_ECOSM;  
Q1RD95, PYRC_ECOUT;  C5BA73, PYRC_EDWI9;  Q3YRI2, PYRC_EHRCJ;  
Q2GH90, PYRC_EHRCR;  B2KCN5, PYRC_ELUMP;  A4W975, PYRC_ENT38;  
Q834E0, PYRC_ENTFA;  B2VDJ8, PYRC_ERWT9;  Q2NCC9, PYRC_ERYLH;  
B7LT74, PYRC_ESCF3;  Q8RG88, PYRC_FUSNN;  B5EB50, PYRC_GEOBB;  
B9M4S4, PYRC_GEODF;  Q5L0U5, PYRC_GEOKA;  B3E3I1, PYRC_GEOLS;  
Q39US3, PYRC_GEOMG;  Q74DP4, PYRC_GEOSL;  C6DZ51, PYRC_GEOSM;  
C5D8P8, PYRC_GEOSW;  A4IM31, PYRC_GEOTN;  A5GF42, PYRC_GEOUR;  
Q2SCE3, PYRC_HAHCH;  A1WV00, PYRC_HALHL;  Q9HMH9, PYRC_HALSA;  
Q17W17, PYRC_HELAH;  Q7VIJ1, PYRC_HELHP;  B6JLG3, PYRC_HELP2;  
B5Z6V2, PYRC_HELPG;  Q1CTU5, PYRC_HELPH;  Q9ZLQ0, PYRC_HELPJ;  
B2UTP7, PYRC_HELPS;  P56465, PYRC_HELPY;  Q5QWC6, PYRC_IDILO;  
Q28RK3, PYRC_JANSC;  B5XXJ5, PYRC_KLEP3;  A6T7D6, PYRC_KLEP7;  
Q5FJB8, PYRC_LACAC;  Q1G867, PYRC_LACDA;  Q047M6, PYRC_LACDB;  
B2GD08, PYRC_LACF3;  Q043B0, PYRC_LACGA;  A8YVZ5, PYRC_LACH4;  
Q74J32, PYRC_LACJO;  Q9CGM7, PYRC_LACLA;  P48795, PYRC_LACLE;  
P77884, PYRC_LACPL;  Q1WVB1, PYRC_LACS1;  Q38X26, PYRC_LACSS;  
C1D672, PYRC_LARHH;  Q6AF87, PYRC_LEIXX;  B1XWS5, PYRC_LEPCP;  
Q92AH1, PYRC_LISIN;  C1KWD6, PYRC_LISMC;  Q71YH9, PYRC_LISMF;  
B8DDR5, PYRC_LISMH;  Q8Y663, PYRC_LISMO;  A0AJU2, PYRC_LISW6;  
B1HQB9, PYRC_LYSSC;  B9EB67, PYRC_MACCJ;  A1U3L1, PYRC_MARAV;  
A6VXW9, PYRC_MARMS;  Q8TSA6, PYRC_METAC;  Q1GYZ0, PYRC_METFK;  
Q58885, PYRC_METJA;  Q8TXX9, PYRC_METKA;  Q8PVF4, PYRC_METMA;  
Q2NHZ6, PYRC_METST;  O27199, PYRC_METTH;  B0JQJ1, PYRC_MICAN;  
Q7U057, PYRC_MYCBO;  Q9CCR4, PYRC_MYCLE;  P9WHL2, PYRC_MYCTO;  
P9WHL3, PYRC_MYCTU;  Q5F9Y1, PYRC_NEIG1;  B4RJT2, PYRC_NEIG2;  
A9M2W6, PYRC_NEIM0;  Q9JVD6, PYRC_NEIMA;  Q9K0D1, PYRC_NEIMB;  
A1KSU5, PYRC_NEIMF;  Q0AFI1, PYRC_NITEC;  Q82WF3, PYRC_NITEU;  
Q3J872, PYRC_NITOC;  Q2G9U3, PYRC_NOVAD;  Q0JJD1, PYRC_ORYSJ;  
Q6D698, PYRC_PECAS;  C6DKU3, PYRC_PECCP;  Q03HB2, PYRC_PEDPA;  
Q3A449, PYRC_PELCD;  A1AS12, PYRC_PELPD;  A5D1A4, PYRC_PELTS;  
Q18C47, PYRC_PEPD6;  Q7N5W0, PYRC_PHOLL;  Q6LPI7, PYRC_PHOPR;  
Q48F12, PYRC_PSE14;  Q15YC5, PYRC_PSEA6;  A6V1R9, PYRC_PSEA7;  
B7UVV3, PYRC_PSEA8;  Q02QZ8, PYRC_PSEAB;  P72170, PYRC_PSEAE;  
Q1IE05, PYRC_PSEE4;  Q4K747, PYRC_PSEF5;  C3KBZ0, PYRC_PSEFS;  
A4XS41, PYRC_PSEMY;  A5VZH8, PYRC_PSEP1;  Q3K7J8, PYRC_PSEPF;  
B0KUE9, PYRC_PSEPG;  Q88NW7, PYRC_PSEPK;  B1J4I2, PYRC_PSEPW;  
Q87XM1, PYRC_PSESM;  Q4ZPJ8, PYRC_PSEU2;  A4VIU5, PYRC_PSEU5;  
A1SX20, PYRC_PSYIN;  Q9UXV6, PYRC_PYRAB;  Q8ZZC7, PYRC_PYRAE;  
Q8U4A0, PYRC_PYRFU;  O57740, PYRC_PYRHO;  Q1LRD4, PYRC_RALME;  
B2UFJ8, PYRC_RALPJ;  Q8Y249, PYRC_RALSO;  B3Q0A1, PYRC_RHIE6;  
Q2KCZ6, PYRC_RHIEC;  Q1MM16, PYRC_RHIL3;  B5ZNS1, PYRC_RHILW;  
Q92SC7, PYRC_RHIME;  C3MF80, PYRC_RHISN;  Q7UNR2, PYRC_RHOBA;  
A4WPB7, PYRC_RHOS5;  Q163V6, PYRC_ROSDO;  Q1AVY7, PYRC_RUBXD;  
Q5LQ43, PYRC_RUEPO;  Q1GFQ7, PYRC_RUEST;  B5F944, PYRC_SALA4;  
A9MH00, PYRC_SALAR;  Q57QJ4, PYRC_SALCH;  B5FL01, PYRC_SALDC;  
B5QY02, PYRC_SALEP;  B5RBD7, PYRC_SALG2;  B4TET5, PYRC_SALHS;  
B4T2Z5, PYRC_SALNS;  Q5PGW5, PYRC_SALPA;  A9N5P9, PYRC_SALPB;  
C0Q845, PYRC_SALPC;  B5BBC6, PYRC_SALPK;  B4TSS5, PYRC_SALSV;  
Q8Z7L2, PYRC_SALTI;  P06204, PYRC_SALTY;  Q9UTI0, PYRC_SCHPO;  
Q9S3S1, PYRC_SERMA;  A8GD09, PYRC_SERP5;  A1S9L6, PYRC_SHEAM;  
B8E4P5, PYRC_SHEB2;  A3D7V9, PYRC_SHEB5;  A6WK08, PYRC_SHEB8;  
A9L3F5, PYRC_SHEB9;  Q12NL3, PYRC_SHEDO;  Q087W5, PYRC_SHEFN;  
B0TRS6, PYRC_SHEHH;  A3QAV2, PYRC_SHELP;  Q8EB40, PYRC_SHEON;  
A8H7J4, PYRC_SHEPA;  A4Y9S5, PYRC_SHEPC;  B8CT15, PYRC_SHEPW;  
A0L0B8, PYRC_SHESA;  A8FZC6, PYRC_SHESH;  Q0HLX7, PYRC_SHESM;  
Q0HRV9, PYRC_SHESR;  A1RGK8, PYRC_SHESW;  B1KEK5, PYRC_SHEWM;  
B2TTK9, PYRC_SHIB3;  Q31ZB7, PYRC_SHIBS;  Q32ES3, PYRC_SHIDS;  
Q0T5X0, PYRC_SHIF8;  Q83RT8, PYRC_SHIFL;  Q3Z354, PYRC_SHISS;  
A6U5N6, PYRC_SINMW;  Q01V55, PYRC_SOLUE;  Q1GT81, PYRC_SPHAL;  
Q5HGN1, PYRC_STAAC;  P65905, PYRC_STAAM;  P65906, PYRC_STAAN;  
Q6GHN4, PYRC_STAAR;  Q6GA12, PYRC_STAAS;  P65907, PYRC_STAAW;  
Q5HPZ0, PYRC_STAEQ;  Q8CPJ6, PYRC_STAES;  Q9KXR3, PYRC_STRCO;  
Q9A071, PYRC_STRP1;  P0DD64, PYRC_STRP3;  Q5XCK2, PYRC_STRP6;  
Q7CNB0, PYRC_STRP8;  Q97QN4, PYRC_STRPN;  P0DD65, PYRC_STRPQ;  
Q8DPQ5, PYRC_STRR6;  Q5LZQ6, PYRC_STRT1;  Q5M4C1, PYRC_STRT2;  
O08357, PYRC_SULAC;  Q9UX05, PYRC_SULSO;  B2V5I6, PYRC_SULSY;  
Q970X5, PYRC_SULTO;  Q2LVI3, PYRC_SYNAS;  A0LK22, PYRC_SYNFM;  
B1XI96, PYRC_SYNP2;  Q7U618, PYRC_SYNPX;  A5GR03, PYRC_SYNR3;  
Q3AYG9, PYRC_SYNS9;  Q3AKY8, PYRC_SYNSC;  P74438, PYRC_SYNY3;  
C5BNK6, PYRC_TERTT;  Q9HIM0, PYRC_THEAC;  P96081, PYRC_THEAQ;  
Q5JJ91, PYRC_THEKO;  Q9WYH0, PYRC_THEMA;  B0KA35, PYRC_THEP3;  
B0K2E8, PYRC_THEPX;  Q8R9R6, PYRC_THETN;  Q97C35, PYRC_THEVO;  
B1GYY7, PYRC_UNCTG;  P31301, PYRC_USTMA;  C5CMK6, PYRC_VARPS;  
A7N655, PYRC_VIBCB;  Q9KL24, PYRC_VIBCH;  Q5E0G4, PYRC_VIBF1;  
B5ETI9, PYRC_VIBFM;  Q87J46, PYRC_VIBPA;  B7VQP0, PYRC_VIBSL;  
Q8D3T9, PYRC_VIBVU;  Q7MFB3, PYRC_VIBVY;  Q5GSJ0, PYRC_WOLTR;  
C0R5K8, PYRC_WOLWR;  P20051, PYRC_YEAST;  A1JN45, PYRC_YERE8;  
A7FH16, PYRC_YERP3;  Q1C6L6, PYRC_YERPA;  B2K767, PYRC_YERPB;  
Q8ZFU4, PYRC_YERPE;  A9R7Y6, PYRC_YERPG;  Q1CI09, PYRC_YERPN;  
A4TLT2, PYRC_YERPP;  Q669K2, PYRC_YERPS;  B1JHH4, PYRC_YERPY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-