ENZYME entry: EC 3.5.3.21

Accepted Name
methylenediurea deaminase
Alternative Name(s)
methylenediurease
Reaction catalysed
2 H(+) + 2 H2O + methylenediurea <=> CO2 + N-(hydroxymethyl)urea + 2 NH4(+)
Comment(s)
The methylenediurea is hydrolyzed and decarboxylated to give an aminated methylurea, which then spontaneously hydrolyzes to hydroxymethylurea. The enzyme from Ochrobactrum anthropi also hydrolyzes dimethylenetriurea and trimethylenetetraurea as well as ureidoglycolate, which is hydrolyzed to urea and glyoxylate, and allantoate, which is hydrolyzed to ureidoglycolate, ammonia and carbon dioxide.
Cross-references
BRENDA	3.5.3.21
EC2PDB	3.5.3.21
ExplorEnz	3.5.3.21
PRIAM enzyme-specific profiles	3.5.3.21
KEGG Ligand Database for Enzyme Nomenclature	3.5.3.21
IUBMB Enzyme Nomenclature	3.5.3.21
IntEnz	3.5.3.21
MEDLINE	Find literature relating to 3.5.3.21
MetaCyc	3.5.3.21
Rhea expert-curated reactions	3.5.3.21

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-