ENZYME entry: EC 3.5.4.30

Accepted Name
dCTP deaminase (dUMP-forming).
Reaction catalysed
dCTP + 2 H(2)O <=> dUMP + diphosphate + NH(3)
Cofactor(s)
Mg(2+).
Comment(s)
  • Is highly specific for dCTP as substrate as dCMP, CTP, CDP, CMP, cytosine or deoxycytosine are not deaminated.
  • While most bacteria require two enzymes to form dUMP from dCTP (EC 3.5.4.13 and EC 3.6.1.23), the archaeon Methanocaldococcus jannaschii uses a single enzyme to carry out both functions.
  • This enzyme can also act as a dUTP diphosphatase, but more slowly.
Cross-references
BRENDA3.5.4.30
EC2PDB3.5.4.30
ExplorEnz3.5.4.30
PRIAM enzyme-specific profiles3.5.4.30
KEGG Ligand Database for Enzyme Nomenclature3.5.4.30
IUBMB Enzyme Nomenclature3.5.4.30
IntEnz3.5.4.30
MEDLINEFind literature relating to 3.5.4.30
MetaCyc3.5.4.30
UniProtKB/Swiss-Prot
Q57872, DCD_METJA

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-