ENZYME entry: EC 3.5.4.37

Accepted Name
Double-stranded RNA adenine deaminase.
Alternative Name(s)
Double-stranded RNA adenosine deaminase.
Double-stranded RNA-specific adenosine deaminase.
DsRNA adenosine deaminase.
Reaction catalysed
Adenine in double-stranded RNA + H(2)O <=> hypoxanthine in double-stranded RNA + NH(3)
Comment(s)
  • This eukaryotic enzyme is involved in RNA editing.
  • It destabilizes double-stranded RNA through conversion of adenosine to inosine.
  • Inositol hexakisphosphate is required for activity.
Cross-references
BRENDA3.5.4.37
EC2PDB3.5.4.37
ExplorEnz3.5.4.37
PRIAM enzyme-specific profiles3.5.4.37
KEGG Ligand Database for Enzyme Nomenclature3.5.4.37
IUBMB Enzyme Nomenclature3.5.4.37
IntEnz3.5.4.37
MEDLINEFind literature relating to 3.5.4.37
MetaCyc3.5.4.37
UniProtKB/Swiss-Prot
P55265, DSRAD_HUMAN;  Q99MU3, DSRAD_MOUSE;  P55266, DSRAD_RAT;  
P78563, RED1_HUMAN;  Q91ZS8, RED1_MOUSE;  P51400, RED1_RAT;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-