ENZYME entry: EC 3.5.4.43

Accepted Name
Hydroxydechloroatrazine ethylaminohydrolase.
Alternative Name(s)
2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase.
Hydroxyatrazine hydrolase.
Reaction catalysed
Hydroxyatrazine + H(2)O <=> N-isopropylammelide + ethylamine
Cofactor(s)
Zn(2+).
Comment(s)
  • This bacterial enzyme is involved in degradation of the herbicide atrazine.
  • The enzyme has a broad substrate range, and requires a monohydroxylated S-triazine ring with a minimum of one primary or secondary amine substituent and either a chloride or amine leaving group.
  • It catalyzes both deamination and dechlorination reactions.
  • Formerly EC 3.5.99.3.
Cross-references
BRENDA3.5.4.43
EC2PDB3.5.4.43
ExplorEnz3.5.4.43
PRIAM enzyme-specific profiles3.5.4.43
KEGG Ligand Database for Enzyme Nomenclature3.5.4.43
IUBMB Enzyme Nomenclature3.5.4.43
IntEnz3.5.4.43
MEDLINEFind literature relating to 3.5.4.43
MetaCyc3.5.4.43
UniProtKB/Swiss-Prot
P95442, ATZB_PSESD

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.4.-
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