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ENZYME entry: EC 3.6.1.17

Accepted Name
Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical).
Alternative Name(s)
Ap(4)A hydrolase.
Ap(4)Aase.
Ap4A hydrolase.
Ap4Aase.
Bis(5'-adenosyl)-tetraphosphatase.
Bis(5'-guanosyl)-tetraphosphatase.
Diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase.
Diadenosinetetraphosphatase (asymmetrical).
Diguanosinetetraphosphatase (asymmetrical).
Dinucleosidetetraphosphatase (asymmetrical).
Reaction catalysed
P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H(2)O <=> GTP + GMP
Comment(s)
Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly, on bis(5'-adenosyl)-tetraphosphate and bis(5'-uridyl)-tetraphosphate (cf. EC 3.6.1.41).
Cross-references
PROSITEPDOC00694 ; PDOC00695
BRENDA3.6.1.17
EC2PDB3.6.1.17
ExplorEnz3.6.1.17
PRIAM enzyme-specific profiles3.6.1.17
KEGG Ligand Database for Enzyme Nomenclature3.6.1.17
IUBMB Enzyme Nomenclature3.6.1.17
IntEnz3.6.1.17
MEDLINEFind literature relating to 3.6.1.17
MetaCyc3.6.1.17
UniProtKB/Swiss-Prot
Q29RJ1, AP4A_BOVIN;  P50583, AP4A_HUMAN;  P56380, AP4A_MOUSE;  
P50584, AP4A_PIG;  Q6PEC0, AP4A_RAT;  P49776, APH1_SCHPO;  
P41250, GARS_HUMAN;  Q9CZD3, GARS_MOUSE;  Q5RBL1, GARS_PONAB;  
Q5I0G4, GARS_RAT;  Q9C6Z2, NUD25_ARATH;  B7GLK2, PRPE_ANOFW;  
C3P3Q5, PRPE_BACAA;  C3LBR5, PRPE_BACAC;  A0RB32, PRPE_BACAH;  
Q81TQ0, PRPE_BACAN;  B7JEP5, PRPE_BACC0;  Q73BU4, PRPE_BACC1;  
B7ILE8, PRPE_BACC2;  C1ELB5, PRPE_BACC3;  B7HGW3, PRPE_BACC4;  
B7I0B6, PRPE_BACC7;  A7GM94, PRPE_BACCN;  B9IU03, PRPE_BACCQ;  
Q81GJ7, PRPE_BACCR;  Q63EG2, PRPE_BACCZ;  Q9K907, PRPE_BACHD;  
Q6HLX9, PRPE_BACHK;  Q65LA0, PRPE_BACLD;  O31614, PRPE_BACSU;  
A7Z3F2, PRPE_BACVZ;  A9VJS5, PRPE_BACWK;  Q5L1R3, PRPE_GEOKA;  
C5D7A6, PRPE_GEOSW;  A4IL88, PRPE_GEOTN;  Q8ERS7, PRPE_OCEIH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
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