ID 3.6.1.45 DE UDP-sugar diphosphatase. AN Nucleosidediphosphate-sugar diphosphatase. AN Nucleosidediphosphate-sugar pyrophosphatase. AN UDP-sugar hydrolase. AN UDP-sugar pyrophosphatase. CA UDP-sugar + H(2)O = UMP + alpha-D-aldose 1-phosphate. CF Divalent cation. CC -!- UDP-sugar is the best substrate, although other nucleoside-sugar CC diphosphates are used as substrates with similar Km values but much CC lower maximum velocities. CC -!- Thus, this enzyme has a specificity distinct from that of CC EC 3.6.1.21. CC -!- Some but not all enzymes of this class also appear to have EC 3.1.3.5 CC activity. PR PROSITE; PDOC00627; DR P52307, 5NTD_BOOMI ; Q9XZ43, 5NTD_LUTLO ; Q05B60, NUD14_BOVIN; DR O95848, NUD14_HUMAN; Q9D142, NUD14_MOUSE; P07024, USHA_ECOLI ; DR Q9RN37, USHA_SALPU ; Q56878, USHA_YERE8 ; //