ENZYME entry: EC 3.6.1.66

Accepted Name
XTP/dITP diphosphatase.
Alternative Name(s)
Hypoxanthine/xanthine dNTP pyrophosphatase.
Reaction catalysed
  • XTP + H(2)O <=> XMP + diphosphate
  • dITP + H(2)O <=> dIMP + diphosphate
Cofactor(s)
Mg(2+).
Comment(s)
The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP and dITP.
Cross-references
BRENDA3.6.1.66
EC2PDB3.6.1.66
ExplorEnz3.6.1.66
PRIAM enzyme-specific profiles3.6.1.66
KEGG Ligand Database for Enzyme Nomenclature3.6.1.66
IUBMB Enzyme Nomenclature3.6.1.66
IntEnz3.6.1.66
MEDLINEFind literature relating to 3.6.1.66
MetaCyc3.6.1.66
UniProtKB/Swiss-Prot
A9NGK2, IXTPA_ACHLI;  A1TT41, IXTPA_ACIAC;  Q6FEQ6, IXTPA_ACIAD;  
B7H0A1, IXTPA_ACIB3;  B7I4X1, IXTPA_ACIB5;  B2I3B3, IXTPA_ACIBC;  
A3M1X9, IXTPA_ACIBT;  C1F8I0, IXTPA_ACIC5;  B9MEJ9, IXTPA_ACIET;  
A1W4I7, IXTPA_ACISJ;  Q8UIG9, IXTPA_AGRFC;  Q2IEX2, IXTPA_ANADE;  
A7HFW2, IXTPA_ANADF;  O66580, IXTPA_AQUAE;  A8ESC9, IXTPA_ARCB4;  
O28046, IXTPA_ARCFU;  Q5P5J5, IXTPA_AROAE;  Q81LB0, IXTPA_BACAN;  
Q72ZT2, IXTPA_BACC1;  Q817P4, IXTPA_BACCR;  Q633V5, IXTPA_BACCZ;  
Q64MG2, IXTPA_BACFR;  Q9K8D9, IXTPA_BACHD;  Q6HD43, IXTPA_BACHK;  
Q65GG3, IXTPA_BACLD;  Q5WEM4, IXTPA_BACSK;  P94558, IXTPA_BACSU;  
Q8A327, IXTPA_BACTN;  Q6G565, IXTPA_BARHE;  Q6G1E6, IXTPA_BARQU;  
Q6MJR8, IXTPA_BDEBA;  B8DVS6, IXTPA_BIFA0;  B3DTK7, IXTPA_BIFLD;  
Q8G7I1, IXTPA_BIFLO;  B7GN27, IXTPA_BIFLS;  Q0SNR4, IXTPA_BORAP;  
Q662B8, IXTPA_BORBP;  Q7WI95, IXTPA_BORBR;  O51263, IXTPA_BORBU;  
B7J1H5, IXTPA_BORBZ;  B5RL72, IXTPA_BORDL;  Q7W6C6, IXTPA_BORPA;  
Q7VXX8, IXTPA_BORPE;  B5RR63, IXTPA_BORRA;  Q89WK5, IXTPA_BRADU;  
A5E8I8, IXTPA_BRASB;  P64305, IXTPA_BRUME;  P64306, IXTPA_BRUSU;  
Q62HZ7, IXTPA_BURMA;  Q63RV4, IXTPA_BURPS;  Q8RC29, IXTPA_CALS4;  
A7ZBP3, IXTPA_CAMC1;  A0RMP5, IXTPA_CAMFF;  A7HZE0, IXTPA_CAMHC;  
A8FN54, IXTPA_CAMJ8;  A7H1W5, IXTPA_CAMJD;  Q9PMS6, IXTPA_CAMJE;  
A1W0Z2, IXTPA_CAMJJ;  Q5HT36, IXTPA_CAMJR;  Q9ABS4, IXTPA_CAUCR;  
Q5L4Q6, IXTPA_CHLAB;  Q821F9, IXTPA_CHLCV;  Q256I5, IXTPA_CHLFF;  
Q9PJD4, IXTPA_CHLMU;  Q9Z7D1, IXTPA_CHLPN;  B0B8I0, IXTPA_CHLT2;  
Q3KL90, IXTPA_CHLTA;  B0BA59, IXTPA_CHLTB;  Q8KFJ6, IXTPA_CHLTE;  
O84611, IXTPA_CHLTR;  Q7NZJ6, IXTPA_CHRVO;  Q97FR2, IXTPA_CLOAB;  
Q8XI68, IXTPA_CLOPE;  Q891I4, IXTPA_CLOTE;  Q6NFN7, IXTPA_CORDI;  
Q8FMU9, IXTPA_COREF;  A4QGQ5, IXTPA_CORGB;  Q8NMR5, IXTPA_CORGL;  
Q4JX01, IXTPA_CORJK;  B1VGW8, IXTPA_CORU7;  Q83FA3, IXTPA_COXBU;  
C1CXX6, IXTPA_DEIDV;  Q1IW81, IXTPA_DEIGD;  Q9RXX6, IXTPA_DEIRA;  
A9BTA7, IXTPA_DELAS;  Q6AQD7, IXTPA_DESPS;  A4J7Y6, IXTPA_DESRM;  
Q726F4, IXTPA_DESVH;  B5YEU3, IXTPA_DICT6;  Q8XCU5, IXTPA_ECO57;  
Q8FE27, IXTPA_ECOL6;  P52061, IXTPA_ECOLI;  B2KEA9, IXTPA_ELUMP;  
B2VEZ3, IXTPA_ERWT9;  B1YJW5, IXTPA_EXIS2;  C4L4I7, IXTPA_EXISA;  
A5FH89, IXTPA_FLAJ1;  A6H0L2, IXTPA_FLAPJ;  Q0RQL6, IXTPA_FRAAA;  
Q5NEQ9, IXTPA_FRATT;  Q5KWI6, IXTPA_GEOKA;  Q74C80, IXTPA_GEOSL;  
Q7NN81, IXTPA_GLOVI;  Q5FRF4, IXTPA_GLUOX;  A0M0C9, IXTPA_GRAFK;  
Q7VLS3, IXTPA_HAEDU;  P44598, IXTPA_HAEIN;  A1WVN6, IXTPA_HALHL;  
Q7VF43, IXTPA_HELHP;  B4U8R9, IXTPA_HYDS0;  A2BJY7, IXTPA_HYPBU;  
Q5QY51, IXTPA_IDILO;  A8A8W1, IXTPA_IGNH4;  B1L6T7, IXTPA_KORCO;  
Q5FLV7, IXTPA_LACAC;  Q74KU4, IXTPA_LACJO;  Q9CG29, IXTPA_LACLA;  
Q88V20, IXTPA_LACPL;  Q5X245, IXTPA_LEGPA;  Q5ZSN3, IXTPA_LEGPH;  
Q5WTW9, IXTPA_LEGPL;  Q6AEL0, IXTPA_LEIXX;  B0SE38, IXTPA_LEPBA;  
B1Y0J8, IXTPA_LEPCP;  Q72UV8, IXTPA_LEPIC;  Q8F031, IXTPA_LEPIN;  
Q03YJ8, IXTPA_LEUMM;  Q92CH0, IXTPA_LISIN;  Q720J0, IXTPA_LISMF;  
Q8Y7N5, IXTPA_LISMO;  Q65RQ6, IXTPA_MANSM;  Q8TJS1, IXTPA_METAC;  
Q602P0, IXTPA_METCA;  B3DV19, IXTPA_METI4;  Q57679, IXTPA_METJA;  
Q8TV07, IXTPA_METKA;  Q8PZ91, IXTPA_METMA;  A2SJB9, IXTPA_METPP;  
D9PYS9, IXTPA_METTM;  B1MLZ4, IXTPA_MYCA9;  P64308, IXTPA_MYCBO;  
P52063, IXTPA_MYCLE;  Q6MT00, IXTPA_MYCMS;  Q73X89, IXTPA_MYCPA;  
Q8EVN6, IXTPA_MYCPE;  P9WMR6, IXTPA_MYCTO;  P9WMR7, IXTPA_MYCTU;  
B2A6I7, IXTPA_NATTJ;  B9L638, IXTPA_NAUPA;  Q9JVG5, IXTPA_NEIMA;  
Q9K0G6, IXTPA_NEIMB;  Q82XJ3, IXTPA_NITEU;  A6Q5H7, IXTPA_NITSB;  
Q5Z0V0, IXTPA_NOCFA;  Q8YM52, IXTPA_NOSS1;  Q8EPJ6, IXTPA_OCEIH;  
B1ZXD5, IXTPA_OPITP;  A6LGA4, IXTPA_PARD8;  Q6MF40, IXTPA_PARUW;  
Q9CKF5, IXTPA_PASMU;  Q6D117, IXTPA_PECAS;  Q3A2Y7, IXTPA_PELCD;  
Q7N7H2, IXTPA_PHOLL;  Q6LML4, IXTPA_PHOPR;  Q6L1H9, IXTPA_PICTO;  
A1VKF6, IXTPA_POLNA;  Q7MUC6, IXTPA_PORGI;  Q6A760, IXTPA_PROAC;  
A2C0B3, IXTPA_PROM1;  Q7VDQ7, IXTPA_PROMA;  Q7V4S3, IXTPA_PROMM;  
Q7V316, IXTPA_PROMP;  Q46H95, IXTPA_PROMT;  Q9I6A8, IXTPA_PSEAE;  
Q88CT0, IXTPA_PSEPK;  Q87V88, IXTPA_PSESM;  Q8ZVB5, IXTPA_PYRAE;  
Q8U446, IXTPA_PYRFU;  O59580, IXTPA_PYRHO;  Q8XXF4, IXTPA_RALSO;  
Q98DN4, IXTPA_RHILO;  Q92SK4, IXTPA_RHIME;  Q7UGM3, IXTPA_RHOBA;  
B6IVK5, IXTPA_RHOCS;  Q21XZ3, IXTPA_RHOFT;  Q6NCY9, IXTPA_RHOPA;  
Q2RN61, IXTPA_RHORT;  Q5LWF7, IXTPA_RUEPO;  Q5PMK9, IXTPA_SALPA;  
Q8Z3U6, IXTPA_SALTI;  Q8ZM45, IXTPA_SALTY;  Q8EBY7, IXTPA_SHEON;  
Q83JS0, IXTPA_SHIFL;  Q5HGT2, IXTPA_STAAC;  P64309, IXTPA_STAAM;  
P99094, IXTPA_STAAN;  Q6GHT4, IXTPA_STAAR;  Q6GA63, IXTPA_STAAS;  
P58995, IXTPA_STAAW;  Q5HQ23, IXTPA_STAEQ;  Q8CSY5, IXTPA_STAES;  
Q8E3V8, IXTPA_STRA3;  Q8DY93, IXTPA_STRA5;  Q82D15, IXTPA_STRAW;  
Q9S2H9, IXTPA_STRCO;  Q8DSQ6, IXTPA_STRMU;  Q9A1B6, IXTPA_STRP1;  
P0DB58, IXTPA_STRP3;  Q5XDP8, IXTPA_STRP6;  Q8P2D2, IXTPA_STRP8;  
P64310, IXTPA_STRPN;  P0DB59, IXTPA_STRPQ;  P64311, IXTPA_STRR6;  
Q5M1I4, IXTPA_STRT1;  Q5M626, IXTPA_STRT2;  Q30UH9, IXTPA_SULDN;  
A6Q6L9, IXTPA_SULNB;  Q97ZZ0, IXTPA_SULSO;  B2V8P5, IXTPA_SULSY;  
Q67SL4, IXTPA_SYMTH;  A0LG38, IXTPA_SYNFM;  Q7U9M0, IXTPA_SYNPX;  
Q0IDG4, IXTPA_SYNS3;  P74432, IXTPA_SYNY3;  Q9HLA4, IXTPA_THEAC;  
Q8DHZ6, IXTPA_THEEB;  Q5JEX8, IXTPA_THEKO;  Q9WY06, IXTPA_THEMA;  
A5IKR2, IXTPA_THEP1;  B0KBM4, IXTPA_THEP3;  B0K3T5, IXTPA_THEPX;  
Q72I42, IXTPA_THET2;  Q5SHS6, IXTPA_THET8;  B5YHP2, IXTPA_THEYD;  
B8GPB3, IXTPA_THISH;  Q73KE7, IXTPA_TREDE;  O83452, IXTPA_TREPA;  
B2S334, IXTPA_TREPS;  Q83HF7, IXTPA_TROW8;  Q83FT2, IXTPA_TROWT;  
A1WQF4, IXTPA_VEREI;  Q9KUQ9, IXTPA_VIBCH;  Q87LJ1, IXTPA_VIBPA;  
Q8DCB9, IXTPA_VIBVU;  Q7MHJ0, IXTPA_VIBVY;  Q8D3C3, IXTPA_WIGBR;  
Q7MR19, IXTPA_WOLSU;  Q8PH61, IXTPA_XANAC;  Q4UY37, IXTPA_XANC8;  
Q8P5T3, IXTPA_XANCP;  Q5H3S6, IXTPA_XANOR;  Q9PD73, IXTPA_XYLFA;  
Q87DG2, IXTPA_XYLFT;  Q8ZHF4, IXTPA_YERPE;  Q666N1, IXTPA_YERPS;  
Q5NRL7, IXTPA_ZYMMO;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-